Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 8/20 | 0.57 |
| ▸ | AKR1B10 | O60218 | 4/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 4/20 | 0.44 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MET | P08581 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27707848 | 0.87 | APP (0.60) | APPHCAR2 | |
| SCHEMBL17459717 | 0.86 | ESR1 (0.49) | APP | |
| SCHEMBL27728337 | 0.82 | ALOX5 (0.52) | APPAKR1B10AKR1B1KDM4EALDH1A1 | |
| SCHEMBL19358965 | 0.80 | APP (0.64) | APPHCAR2 | |
| SCHEMBL19358963 | 0.80 | APP (0.64) | APPHCAR2 | |
| SCHEMBL1405663 | 0.79 | KDM4E (0.46) | APPKDM4EALDH1A1 | |
| SCHEMBL27861984 | 0.78 | ALOX5 (0.48) | — | |
| SCHEMBL1259776 | 0.77 | PTPN1 (0.42) | APPKDM4EALDH1A1 | |
| SCHEMBL27983290 | 0.77 | ALOX5 (0.47) | — | |
| SCHEMBL19358961 | 0.77 | APP (0.63) | APPAKR1B10AKR1B1HCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016012797-A1 | ANTI-DANDRUFF COMPOSITION | CRODA INTERNATIONAL PLC (GB) | 2016-01-28 | — | — | WO | disclosed |
| US-5908615-A | Ferulic acid ester antioxidant/UV absorbent | TSUNO FOOD INDUSTRIAL CO., LTD. (JP) | 1999-06-01 | — | — | US | disclosed |