Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CFTR | P13569 | 3/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.43 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.43 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14803669 | 0.85 | KDM4E (0.53) | KDM4ETDP1MAP2K1L3MBTL1PKM | |
| SCHEMBL3694218 | 0.84 | KDM4E (0.44) | KDM4ETDP1MAP2K1HDAC6L3MBTL1 | |
| SCHEMBL27853426 | 0.83 | HDAC6 (0.45) | KDM4ETDP1HDAC6L3MBTL1POLB | |
| SCHEMBL28024019 | 0.83 | HDAC6 (0.45) | KDM4ETDP1HDAC6L3MBTL1PKM | |
| SCHEMBL4372942 | 0.83 | HDAC6 (0.51) | KDM4ETDP1HDAC6POLBLMNA | |
| SCHEMBL30785815 | 0.83 | KDM4E (0.55) | KDM4EHDAC6L3MBTL1POLBLMNA | |
| SCHEMBL3662007 | 0.83 | KDM4E (0.55) | KDM4EHDAC6L3MBTL1POLBLMNA | |
| SCHEMBL18033657 | 0.81 | HDAC6 (0.48) | KDM4ETDP1HDAC6L3MBTL1POLB | |
| SCHEMBL28776329 | 0.81 | HDAC6 (0.43) | KDM4ETDP1HDAC6L3MBTL1PKM | |
| SCHEMBL27764496 | 0.80 | HDAC6 (0.50) | KDM4ETDP1HDAC6L3MBTL1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3081263-A | — | — | None | — | — | JP | disclosed |
| CN-118703012-B | Composite membrane suitable for Prussian blue positive electrode material, and preparation method and application thereof | 太仓中科赛诺新能源科技有限公司 | 2024-11-15 | — | — | CN | disclosed |
| CN-118589053-B | Sodium ion battery electrolyte and preparation method and application thereof | 太仓中科赛诺新能源科技有限公司 | 2024-10-11 | — | — | CN | disclosed |
| CN-118703012-A | Composite membrane suitable for Prussian blue positive electrode material, and preparation method and application thereof | 太仓中科赛诺新能源科技有限公司 | 2024-09-27 | — | — | CN | disclosed |
| CN-118589053-A | Sodium ion battery electrolyte and preparation method and application thereof | 太仓中科赛诺新能源科技有限公司 | 2024-09-03 | — | — | CN | disclosed |
| CN-116818822-A | Nuclear magnetic resonance method for quantifying glutathione in living cells through reversible reaction | 南开大学 | 2023-09-29 | — | — | CN | disclosed |
| WO-2023097386-A1 | SELECTIVE HDAC6-INHIBITING N-ACYLHYDRAZONE COMPOUNDS, METHODS FOR PRODUCING SAME, COMPOSITIONS, USES, TREATMENT METHODS AND KITS | EUROFARMA LABORATÓRIOS S.A (BR) | 2023-06-08 | — | — | WO | disclosed |
| CN-114957217-A | Compound containing 2-trifluoromethyl picolinamide structure, preparation method and application thereof, herbicide and application thereof | 华中师范大学 | 2022-08-30 | — | — | CN | disclosed |
| EP-2432776-B1 | METHYL SULFANYL PYRIMIDINES USEFUL AS ANTIINFLAMMATORIES, ANALGESICS, AND ANTIEPILEPTICS | UNIV LAVAL (CA) | 2019-09-11 | — | — | EP | disclosed |
| EP-2432776-B1 | METHYL SULFANYL PYRIMIDINES USEFUL AS ANTIINFLAMMATORIES, ANALGESICS, AND ANTIEPILEPTICS | UNIV LAVAL (CA) | 2019-09-11 | — | — | EP | disclosed |
| US-20100298336-A1 | PYRIMIDINES AS NOVEL THERAPEUTIC AGENTS | UNIVERSITE LAVAL (CA) | 2010-11-25 | — | — | US | disclosed |
| US-20100298336-A1 | PYRIMIDINES AS NOVEL THERAPEUTIC AGENTS | UNIVERSITE LAVAL (CA) | 2010-11-25 | — | — | US | disclosed |
| US-20100298336-A1 | PYRIMIDINES AS NOVEL THERAPEUTIC AGENTS | UNIVERSITE LAVAL (CA) | 2010-11-25 | — | — | US | disclosed |
| WO-2010132999-A1 | METHYL SULFANYL PYRMIDMES USEFUL AS ANTIINFLAMMATORIES, ANALGESICS, AND ANTIEPILEPTICS | CHLORION PHARMA, INC. (CA) | 2010-11-25 | — | — | WO | disclosed |
| CN-1143849-C | Pyridine ketones useful as herbicides | �����ɷ� | 2004-03-31 | — | — | CN | disclosed |
| CN-1026455-C | 2, 6-substituted pyridine compounds | MONSANTO CO (US) | 1994-11-09 | — | — | CN | disclosed |
| JP-H0381263-A | 2-TRIFLUOROMETHYLNICOTINIC ACID DERIVATIVE | ISHIHARA SANGYO KAISHA LTD | 1991-04-05 | — | — | JP | disclosed |
| CN-88100822-A | Be used as 2,6 one substituted pyridine compound and herbicidal methods thereof of the replacement of weedicide | — | 1988-09-14 | — | — | CN | disclosed |
| CN-88100828-A | Substituted 2, 6-substituted pyridine compounds | — | 1988-08-24 | — | — | CN | disclosed |
| CN-87103523-A | The 5-sulfur substituted pyriding monocarboxylic herbicides | — | 1987-12-09 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100298336-A1 | PYRIMIDINES AS NOVEL THERAPEUTIC AGENTS | TYMS, P2RX2, TYMP | KDM4E 3841/4885TDP1 425/4885MAP2K1 2550/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.