⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2611831 | 0.77 | — | — | |
| SCHEMBL6308345 | 0.77 | — | — | |
| Hydrochloric Acid SCHEMBL2678647 | 0.74 | — | — | |
| SCHEMBL21737711 | 0.72 | — | — | |
| SCHEMBL20844132 | 0.72 | — | — | |
| SCHEMBL5153254 | 0.72 | — | — | |
| SCHEMBL4591310 | 0.69 | — | — | |
| SCHEMBL21720446 | 0.69 | ALDH1A1 (0.32) | — | |
| SCHEMBL15292239 | 0.69 | KMT2A (0.38) | — | |
| SCHEMBL3267616 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113620902-B | Preparation of 2-chloro-5-chloro-methylthiazole in tower reactor | 邯郸市瑞田农药有限公司 | 2023-08-18 | — | — | CN | claimed |
| CN-113620902-A | Preparation of 2-chloro-5-chloro-methylthiazole by tower reactor | 邯郸市瑞田农药有限公司 | 2021-11-09 | — | — | CN | claimed |
| EP-4273147-A1 | SUBSTITUTED SPIROLACTAMS, SALTS THEREOF AND THEIR USE AS HERBICIDALLY ACTIVE SUBSTANCES | Bayer Aktiengesellschaft (DE) | 2023-11-08 | — | — | EP | disclosed |
| CN-113620902-B | Preparation of 2-chloro-5-chloro-methylthiazole in tower reactor | 邯郸市瑞田农药有限公司 | 2023-08-18 | — | — | CN | disclosed |
| WO-2023107547-A2 | AZETIDINE AND SPIROAZETIDINE COMPOUNDS AND USES THEREOF | Kineta, Inc. (US) | 2023-06-15 | — | — | WO | disclosed |
| WO-2023092781-A1 | PREPARATION METHOD FOR REVERSE OSMOSIS MEMBRANE, AND REVERSE OSMOSIS MEMBRANE PREPARED THEREBY | 沃顿科技股份有限公司 | 2023-06-01 | — | — | WO | disclosed |
| CN-116159449-A | Method for preparing reverse osmosis membrane and reverse osmosis membrane prepared by same | 沃顿科技股份有限公司 | 2023-05-26 | — | — | CN | disclosed |
| CN-113620902-A | Preparation of 2-chloro-5-chloro-methylthiazole by tower reactor | 邯郸市瑞田农药有限公司 | 2021-11-09 | — | — | CN | disclosed |
| CN-113620902-A | Preparation of 2-chloro-5-chloro-methylthiazole by tower reactor | 邯郸市瑞田农药有限公司 | 2021-11-09 | — | — | CN | disclosed |
| WO-2021001528-A1 | NOVEL GALACTOSIDE INHIBITOR OF GALECTINS | GALECTO BIOTECH AB (SE) | 2021-01-07 | — | — | WO | disclosed |
| EP-0942909-A1 | BICYCLIC AMINE DERIVATIVES | ZENECA LIMITED (GB) | 1999-09-22 | — | — | EP | disclosed |
| WO-1998045279-A1 | PREPARATION OF THIAZOLES USING 1,3-DIHALOPROPENES | REILLY INDUSTRIES, INC. (US) | 1998-10-15 | — | — | WO | disclosed |
| WO-1998022463-A1 | BICYCLIC AMINE DERIVATIVES | ZENECA LIMITED (GB) | 1998-05-28 | — | — | WO | disclosed |