Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 15/20 | 0.46 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8443328 | 0.88 | CYP19A1 (0.55) | CYP19A1MAPT | |
| SCHEMBL8443386 | 0.85 | CYP19A1 (0.43) | CYP19A1KCNJ1KCNH2VCAM1 | |
| SCHEMBL8443364 | 0.84 | CYP19A1 (0.53) | CYP19A1 | |
| SCHEMBL5442082 | 0.84 | CYP19A1 (0.43) | CYP19A1KCNJ1KCNH2PGRMAPT | |
| SCHEMBL8442893 | 0.82 | CYP19A1 (0.72) | CYP19A1 | |
| SCHEMBL8446596 | 0.80 | CYP19A1 (0.41) | CYP19A1KCNJ1KCNH2PGRMAPT | |
| SCHEMBL8443728 | 0.80 | CYP19A1 (0.69) | CYP19A1KCNJ1KCNH2 | |
| SCHEMBL5998477 | 0.80 | KMT2A (0.43) | CYP19A1KCNJ1KCNH2MAPTTHRB | |
| SCHEMBL8446288 | 0.78 | CYP19A1 (0.44) | CYP19A1MAPTVCAM1 | |
| SCHEMBL31257790 | 0.78 | MEN1 (0.61) | CYP19A1KCNJ1KCNH2PGRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0641785-B1 | TRIAZOLYLATED TERTIARY AMINE COMPOUND OR SALT THEREOF | YAMANOUCHI PHARMA CO LTD (JP) | 1999-10-27 | — | — | EP | disclosed |
| US-5674886-A | AROMATASE INHIBITOR; BREAST CANCER; UROGENITAL DISORDERS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1997-10-07 | — | — | US | disclosed |
| EP-0641785-A1 | TRIAZOLYLATED TERTIARY AMINE COMPOUND OR SALT THEREOF | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1995-03-08 | — | — | EP | disclosed |