Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 12/20 | 0.44 |
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MERTK | Q12866 | 1/20 | 0.37 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8445502 | 0.78 | CYP19A1 (0.46) | CYP19A1MAPTVCAM1 | |
| SCHEMBL429783 | 0.76 | VCAM1 (0.54) | MAPTPOLBKMT2AALDH1A1CYP1A2 | |
| SCHEMBL8443386 | 0.75 | CYP19A1 (0.43) | CYP19A1VCAM1 | |
| SCHEMBL8443364 | 0.74 | CYP19A1 (0.53) | CYP19A1 | |
| SCHEMBL8845370 | 0.70 | MAPT (0.41) | CYP19A1MAPTPOLBKMT2AALDH1A1 | |
| SCHEMBL2249706 | 0.68 | VCAM1 (0.58) | MAPTKMT2AMERTKVCAM1 | |
| SCHEMBL7287829 | 0.66 | MAPT (0.51) | MAPTPOLBKMT2AALDH1A1CYP1A2 | |
| SCHEMBL8443328 | 0.66 | CYP19A1 (0.55) | CYP19A1MAPTKMT2AALDH1A1CYP1A2 | |
| SCHEMBL1725909 | 0.66 | HCAR3 (0.48) | MAPTPOLBKMT2AALDH1A1CYP1A2 | |
| SCHEMBL12190700 | 0.65 | MAPT (0.50) | MAPTPOLBKMT2AALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0641785-B1 | TRIAZOLYLATED TERTIARY AMINE COMPOUND OR SALT THEREOF | YAMANOUCHI PHARMA CO LTD (JP) | 1999-10-27 | — | — | EP | disclosed |
| EP-0641785-A1 | TRIAZOLYLATED TERTIARY AMINE COMPOUND OR SALT THEREOF | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1995-03-08 | — | — | EP | disclosed |