Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 19/20 | 0.43 |
| ▸ | RXRB | P28702 | 11/20 | 0.42 |
| ▸ | RXRG | P48443 | 11/20 | 0.42 |
| ▸ | RARG | P13631 | 9/20 | 0.42 |
| ▸ | RARB | P10826 | 7/20 | 0.42 |
| ▸ | RARA | P10276 | 5/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8448947 | 1.00 | RXRA (0.43) | RXRARXRBRXRGRARGRARB | |
| SCHEMBL8445537 | 1.00 | RXRA (0.43) | RXRARXRBRXRGRARGRARB | |
| SCHEMBL8308377 | 0.93 | RXRA (0.52) | RXRARXRBRXRGRARGRARB | |
| SCHEMBL8308372 | 0.93 | RXRA (0.52) | RXRARXRBRXRGRARGRARB | |
| SCHEMBL8309368 | 0.93 | RXRA (0.52) | RXRARXRBRXRGRARGRARB | |
| SCHEMBL8308382 | 0.93 | RXRA (0.52) | RXRARXRBRXRGRARGRARB | |
| SCHEMBL8310967 | 0.93 | RXRA (0.52) | RXRARXRBRXRGRARGRARB | |
| SCHEMBL8309367 | 0.93 | RXRA (0.52) | RXRARXRBRXRGRARGRARB | |
| SCHEMBL8308333 | 0.93 | RXRA (0.50) | RXRARXRBRXRGRARGRARB | |
| SCHEMBL8309073 | 0.93 | RXRA (0.50) | RXRARXRBRXRGRARGRARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0933351-A1 | Tricyclic retinoids, methods for their production and use | LIGAND PHARMACEUTICALS INCORPORATED (US) | 1999-08-04 | — | — | EP | claimed |
| EP-0800504-A1 | TRICYCLIC RETINOIDS, METHODS FOR THEIR PRODUCTION AND USE | LIGAND PHARMACEUTICALS, INC. (US) | 1997-10-15 | — | — | EP | claimed |
| WO-1996020914-A1 | TRICYCLIC RETINOIDS, METHODS FOR THEIR PRODUCTION AND USE | LIGAND PHARMACEUTICALS INCORPORATED (US) | 1996-07-11 | — | — | WO | claimed |
| EP-0933351-A1 | Tricyclic retinoids, methods for their production and use | LIGAND PHARMACEUTICALS INCORPORATED (US) | 1999-08-04 | — | — | EP | disclosed |
| EP-0933350-A1 | Tricyclic retinoids, methods for their production and use | LIGAND PHARMACEUTICALS INCORPORATED (US) | 1999-08-04 | — | — | EP | disclosed |
| EP-0800504-A1 | TRICYCLIC RETINOIDS, METHODS FOR THEIR PRODUCTION AND USE | LIGAND PHARMACEUTICALS, INC. (US) | 1997-10-15 | — | — | EP | disclosed |
| WO-1996020914-A1 | TRICYCLIC RETINOIDS, METHODS FOR THEIR PRODUCTION AND USE | LIGAND PHARMACEUTICALS INCORPORATED (US) | 1996-07-11 | — | — | WO | disclosed |