SCHEMBL8445586

SCHEMBL8445586

Nc1ccc(OOC(=O)c2cccc(C(=O)OOc3ccc(N)cc3)c2)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP10 Q53GL7 3/20 0.42
MAPT P10636 5/20 0.41
KMT2A Q03164 4/20 0.41
MEN1 O00255 3/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
MITF O75030 1/20 0.41
ALDH1A1 P00352 1/20 0.41
GAA P10253 1/20 0.41
GFER P55789 1/20 0.41
NLRP1 Q9C000 1/20 0.41
NOD2 Q9HC29 1/20 0.41
F2 P00734 3/20 0.41
LMNA P02545 2/20 0.41
PRSS1 P07477 2/20 0.41
PRSS2 P07478 2/20 0.41
PRSS3 P35030 2/20 0.41
PKM P14618 1/20 0.41
LOXL2 Q9Y4K0 1/20 0.40
NR1H4 Q96RI1 1/20 0.40
TDP1 Q9NUW8 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8445589 0.94 AKR1C3 (0.44) KMT2AGAAF2LMNA
SCHEMBL29221160 0.87 F2 (0.57) PARP10MAPTKMT2AMEN1SMN1; SMN2
SCHEMBL8445592 0.85 KMT2A (0.54) PARP10MAPTKMT2AMEN1SMN1; SMN2
SCHEMBL28453196 0.85 F2 (0.53) PARP10MAPTKMT2AALDH1A1GAA
SCHEMBL27769736 0.79 PARP10 (0.51) PARP10MAPTKMT2AMEN1SMN1; SMN2
SCHEMBL29846109 0.79 KMT2A (0.51) PARP10MAPTKMT2AMEN1SMN1; SMN2
SCHEMBL707848 0.79 KMT2A (0.51) PARP10MAPTKMT2AMEN1SMN1; SMN2
SCHEMBL22826275 0.78 MAPT (0.49) PARP10MAPTKMT2AMEN1SMN1; SMN2
SCHEMBL14552344 0.78 KMT2A (0.55) PARP10MAPTKMT2AMEN1SMN1; SMN2
SCHEMBL10560176 0.77 F2 (0.70) PARP10MAPTKMT2AMEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0948570-A1 METHOD FOR PREPARING LIGHT-ABSORBING POLYMERIC COMPOSITIONS EASTMAN CHEMICAL COMPANY (US) 1999-10-13 EP disclosed
WO-1998023690-A9 METHOD FOR PREPARING LIGHT-ABSORBING POLYMERIC COMPOSITIONS 1998-09-17 WO disclosed
WO-1998023690-A1 METHOD FOR PREPARING LIGHT-ABSORBING POLYMERIC COMPOSITIONS EASTMAN CHEMICAL COMPANY (US) 1998-06-04 WO disclosed