Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FURIN | P09958 | 6/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | F10 | P00742 | 1/20 | 0.52 |
| ▸ | PARP1 | P09874 | 1/20 | 0.50 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8446705 | 1.00 | FURIN (0.56) | FURINMEN1KMT2AF10PARP1 | |
| SCHEMBL6149232 | 1.00 | FURIN (0.56) | FURINMEN1KMT2AF10PARP1 | |
| SCHEMBL5442050 | 1.00 | FURIN (0.56) | FURINMEN1KMT2AF10PARP1 | |
| SCHEMBL5973917 | 1.00 | FURIN (0.56) | FURINMEN1KMT2AF10PARP1 | |
| SCHEMBL5973945 | 0.98 | FURIN (0.56) | FURINMEN1KMT2AF10PARP1 | |
| SCHEMBL6150719 | 0.95 | FURIN (0.56) | FURINMEN1KMT2AF10PARP1 | |
| SCHEMBL5973841 | 0.93 | FURIN (0.55) | FURINMEN1KMT2AF10PARP1 | |
| SCHEMBL5974478 | 0.93 | FURIN (0.55) | FURINMEN1KMT2AF10PARP1 | |
| SCHEMBL4914693 | 0.93 | FURIN (0.55) | FURINMEN1KMT2AF10PARP1 | |
| SCHEMBL5974904 | 0.93 | FURIN (0.55) | FURINMEN1KMT2AF10PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0746312-A4 | GUANYLHYDRAZONES FOR TREATING INFLAMMATORY CONDITIONS | PICOWER INST MED RES (US) | 1999-05-26 | — | — | EP | disclosed |
| EP-0746312-A1 | GUANYLHYDRAZONES FOR TREATING INFLAMMATORY CONDITIONS | THE PICOWER INSTITUTE FOR MEDICAL RESEARCH (US) | 1996-12-11 | — | — | EP | disclosed |
| WO-1995019767-A1 | GUANYLHYDRAZONES FOR TREATING INFLAMMATORY CONDITIONS | THE PICOWER INSTITUTE FOR MEDICAL RESEARCH (US) | 1995-07-27 | — | — | WO | disclosed |