Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 14/20 | 0.41 |
| ▸ | HTR2A | P28223 | 4/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7454400 | 0.86 | USP30 (0.47) | HTR2ATDP1 | |
| SCHEMBL8447182 | 0.86 | USP30 (0.47) | HTR2ATDP1 | |
| Hydrochloric Acid SCHEMBL7464662 | 0.85 | USP30 (0.47) | HTR2ATDP1 | |
| SCHEMBL8448555 | 0.85 | ALDH1A1 (0.39) | HTR2ATDP1 | |
| SCHEMBL8444895 | 0.85 | ALDH1A1 (0.39) | HTR2ATDP1 | |
| Hydrochloric Acid SCHEMBL8447217 | 0.83 | TDP1 (0.38) | HTR2ATDP1 | |
| SCHEMBL27390601 | 0.82 | ALDH1A1 (0.41) | CCR5HTR2ATDP1 | |
| Hydrochloric Acid SCHEMBL8447164 | 0.82 | TDP1 (0.37) | HTR2ATDP1 | |
| Hydrochloric Acid SCHEMBL8445717 | 0.82 | ALDH1A1 (0.40) | CCR5HTR2ATDP1 | |
| Hydrochloric Acid SCHEMBL8448896 | 0.82 | IDO1 (0.38) | TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1093861-C | 1-methylcarbapenem derivatives | SANKYO CO (JP) | 2002-11-06 | — | — | CN | disclosed |
| US-5977097-A | 1-methylcarbapenem derivatives | SANKYO COMPANY LIMITED (JP) | 1999-11-02 | — | — | US | disclosed |
| EP-0900797-A1 | 1-METHYLCARBAPENEM DERIVATIVES | SANKYO COMPANY LIMITED (JP) | 1999-03-10 | — | — | EP | disclosed |