Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | STAT1 | P42224 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 5/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | GLS | O94925 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8445698 | 1.00 | TSHR (0.47) | TSHRMAPK1ALDH1A1RAB9ANPC1 | |
| SCHEMBL2877170 | 0.83 | GAA (0.43) | MAPK1ALDH1A1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL2877169 | 0.83 | GAA (0.43) | MAPK1ALDH1A1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL2877172 | 0.83 | GAA (0.43) | MAPK1ALDH1A1RAB9ANPC1SMN1; SMN2 | |
| Potassium SCHEMBL8627342 | 0.82 | GAA (0.43) | MAPK1ALDH1A1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL8627333 | 0.82 | GAA (0.43) | MAPK1ALDH1A1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL8575344 | 0.81 | HDAC3 (0.39) | MAPK1ALDH1A1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL12333890 | 0.81 | MAPT (0.48) | MAPK1RAB9ANPC1SMN1; SMN2GAA | |
| SCHEMBL19426145 | 0.79 | TSHR (0.42) | TSHRMAPK1ALDH1A1RAB9ANPC1 | |
| SCHEMBL2450269 | 0.78 | MAPT (0.45) | MAPK1RAB9ANPC1SMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0594263-B1 | INTERMEDIATES FOR THE PREPARATION OF THIOALKYLTHIO CEPHALOSPORIN DERIVATIVES | SHIONOGI & CO (JP) | 1999-06-09 | — | — | EP | disclosed |
| EP-0594263-A1 | Thioalkylthio cephalosporin derivatives and intermediates | SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD. (JP) | 1994-04-27 | — | — | EP | disclosed |