SCHEMBL8445709

SCHEMBL8445709

O=c1[nH]c2c(CC#CI)cccc2o1

nearest known ligand 0.41

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
MCL1 Q07820 1/20 0.41
GRM5 P41594 13/20 0.40
OGT O15294 1/20 0.40
EPHX2 P34913 5/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9275325 0.84 MCL1 (0.41) MCL1GRM5OGTEPHX2
SCHEMBL19153870 0.78 MCL1 (0.46) MCL1GRM5OGTEPHX2
SCHEMBL1704671 0.78 LMNA (0.36) GRM5
SCHEMBL28626037 0.77 MCL1 (0.49) MCL1GRM5OGTEPHX2
SCHEMBL30114950 0.77 MCL1 (0.49) MCL1GRM5OGTEPHX2
SCHEMBL5536069 0.77 MCL1 (0.45) MCL1GRM5OGTEPHX2
SCHEMBL27371232 0.77 MCL1 (0.45) MCL1GRM5OGTEPHX2
SCHEMBL5537757 0.74 MCL1 (0.42) MCL1GRM5OGTEPHX2
SCHEMBL27399312 0.74 MCL1 (0.42) MCL1GRM5OGTEPHX2
SCHEMBL30416222 0.74 MCL1 (0.42) MCL1GRM5OGTEPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6008244-A APPLYING ONTO OR INTO THE MARINE STRUCTURE TO INHIBIT GROWTH SUCH AS SOFT CORALS, TUNICATES, HYDROIDS, SPONGES, ANEMONES, BARNACLES, TUBEWORMS AND MOLLUSCS ROHM AND HAAS COMPANY (US) 1999-12-28 US disclosed
EP-0835604-A1 Halopropargyl compounds as marine antifouling agents ROHM AND HAAS COMPANY (US) 1998-04-15 EP disclosed