Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | QPCT | Q16769 | 2/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.42 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | IKBKB | O14920 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8443909 | 0.99 | ALOX15 (0.47) | ALOX15HSD17B10LMNAPOLBQPCT | |
| SCHEMBL8444374 | 0.91 | ALOX15 (0.55) | ALOX15HSD17B10LMNAPOLBQPCT | |
| SCHEMBL8443654 | 0.87 | HSD17B10 (0.49) | ALOX15HSD17B10LMNAPOLBQPCT | |
| SCHEMBL8443077 | 0.86 | ALOX15 (0.46) | ALOX15HSD17B10LMNAPOLBQPCT | |
| SCHEMBL27288444 | 0.84 | ALOX15 (0.47) | ALOX15HSD17B10LMNAPOLBQPCT | |
| SCHEMBL8444551 | 0.83 | CYP19A1 (0.57) | HSD17B10LMNAPOLBQPCTCYP19A1 | |
| SCHEMBL8445916 | 0.83 | QPCT (0.54) | LMNAPOLBQPCTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL8444444 | 0.82 | QPCT (0.53) | LMNAPOLBQPCTSMN1; SMN2 | |
| SCHEMBL8444476 | 0.81 | KMT2A (0.56) | ALOX15HSD17B10LMNAPOLBQPCT | |
| SCHEMBL8446230 | 0.80 | ALOX15 (0.48) | ALOX15HSD17B10LMNAPOLBQPCT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5547972-A | 1-(ARLALKYLAMINOALKYL) IMIDAZOLE DERIVATIVES | THE BOOTS COMPANY PLC (GB) | 1996-08-20 | — | — | US | claimed |
| EP-0618907-B1 | 1-(ARYLALKYL-AMINOALKYL)IMIDAZOLE DERIVATIVES, PROCESSES OF PREPARATION AND USE AS THERAPEUTICAL AGENTS | BRITISH TECH GROUP INT (GB) | 1999-04-28 | — | — | EP | disclosed |
| US-5547972-A | 1-(ARLALKYLAMINOALKYL) IMIDAZOLE DERIVATIVES | THE BOOTS COMPANY PLC (GB) | 1996-08-20 | — | — | US | disclosed |
| WO-1995022327-A1 | USE OF 1-(ARYLALKYLAMINOALKYL) IMIDAZOLES FOR TREATING NEUROLOGICAL DAMAGE | KNOLL AG (DE) | 1995-08-24 | — | — | WO | disclosed |
| CN-1096781-A | The therapeutical agent that contains 1-(aralkyl-aminoalkyl) imidazolium compounds | BOOTS CO PLC (GB) | 1994-12-28 | — | — | CN | disclosed |
| EP-0618907-A1 | 1-(ARYLALKYL-AMINOALKYL)IMIDAZOLE DERIVATIVES, PROCESSES OF PREPARATION AND USE AS THERAPEUTICAL AGENTS | Knoll AG (DE) | 1994-10-12 | — | — | EP | disclosed |
| WO-1993013075-A1 | 1-(ARYLALKYL-AMINOALKYL)IMIDAZOLE DERIVATIVES, PROCESSES OF PREPARATION AND USE AS THERAPEUTICAL AGENTS | THE BOOTS COMPANY PLC (GB) | 1993-07-08 | — | — | WO | disclosed |