Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.67 |
| ▸ | HTR2A | P28223 | 1/20 | 0.53 |
| ▸ | LTA4H | P09960 | 2/20 | 0.53 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.53 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22766219 | 0.98 | MAOA (0.64) | MAOAHTR2ALTA4HPLA2G2AFFAR1 | |
| SCHEMBL8638619 | 0.98 | MAOA (0.64) | MAOAHTR2ALTA4HPLA2G2AFFAR1 | |
| SCHEMBL2025420 | 0.94 | MAOA (0.57) | MAOAHTR2ALTA4HPLA2G2AFFAR1 | |
| SCHEMBL19322272 | 0.90 | FFAR1 (0.62) | LTA4HFFAR1MAOB | |
| SCHEMBL19322285 | 0.88 | FFAR1 (0.60) | LTA4HFFAR1MAOB | |
| SCHEMBL19322269 | 0.88 | FFAR1 (0.60) | LTA4HFFAR1MAOB | |
| SCHEMBL19322273 | 0.88 | FFAR1 (0.60) | LTA4HFFAR1MAOB | |
| SCHEMBL740325 | 0.86 | HTR2A (0.62) | MAOAHTR2ALTA4HPLA2G2AFFAR1 | |
| SCHEMBL12040543 | 0.86 | FFAR1 (0.58) | MAOALTA4HFFAR1MAOB | |
| SCHEMBL28527968 | 0.86 | HTR2A (0.62) | MAOAHTR2ALTA4HPLA2G2AFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0618907-B1 | 1-(ARYLALKYL-AMINOALKYL)IMIDAZOLE DERIVATIVES, PROCESSES OF PREPARATION AND USE AS THERAPEUTICAL AGENTS | BRITISH TECH GROUP INT (GB) | 1999-04-28 | — | — | EP | disclosed |
| US-5614614-A | ANTIBIOTICS, CHEMICAL INTERMEDIATES | ROUSSEL UCLAF (FR) | 1997-03-25 | — | — | US | disclosed |
| US-5527780-A | BACTERICIDES | ROUSSEL UCLAF (FR) | 1996-06-18 | — | — | US | disclosed |
| EP-0596802-B1 | Erythromycin derivatives, their process of preparation and their application as medicaments | ROUSSEL UCLAF (FR) | 1996-03-20 | — | — | EP | disclosed |
| EP-0596802-A1 | Erythromycin derivatives, their process of preparation and their application as medicaments | ROUSSEL UCLAF (FR) | 1994-05-11 | — | — | EP | disclosed |