Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3A | Q14432 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | BLM | P54132 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | VCP | P55072 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | HBB | P68871 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | PNP | P00491 | 3/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | EDNRA | P25101 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8449385 | 0.93 | PDE3A (0.54) | PDE3AMEN1KMT2ABLMALDH1A1 | |
| SCHEMBL8445379 | 0.90 | HPRT1 (0.43) | PDE3AMEN1KMT2AHBBMAPK1 | |
| SCHEMBL9583316 | 0.87 | MEN1 (0.62) | PDE3AMEN1KMT2ABLMALDH1A1 | |
| SCHEMBL9584449 | 0.87 | MEN1 (0.62) | PDE3AMEN1KMT2ABLMALDH1A1 | |
| SCHEMBL9583576 | 0.87 | MEN1 (0.62) | PDE3AMEN1KMT2ABLMALDH1A1 | |
| SCHEMBL9584195 | 0.87 | MEN1 (0.62) | PDE3AMEN1KMT2ABLMALDH1A1 | |
| SCHEMBL9583399 | 0.87 | MEN1 (0.62) | PDE3AMEN1KMT2ABLMALDH1A1 | |
| SCHEMBL9584235 | 0.87 | MEN1 (0.62) | PDE3AMEN1KMT2ABLMALDH1A1 | |
| SCHEMBL9583116 | 0.87 | MEN1 (0.62) | PDE3AMEN1KMT2ABLMALDH1A1 | |
| SCHEMBL9583698 | 0.87 | MEN1 (0.62) | PDE3AMEN1KMT2ABLMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0942916-A2 | NUCLEOSIDES | Medivir Aktiebolag (SE) | 1999-09-22 | — | — | EP | disclosed |
| WO-1998021223-A1 | NUCLEOSIDES | MEDIVIR AB (SE) | 1998-05-22 | — | — | WO | disclosed |