Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPRT1 | P00492 | 8/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HBB | P68871 | 1/20 | 0.41 |
| ▸ | TK1 | P04183 | 1/20 | 0.40 |
| ▸ | PNP | P00491 | 4/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8450120 | 0.94 | HPRT1 (0.42) | HPRT1PDE3AMEN1KMT2AMAPK1 | |
| SCHEMBL8447927 | 0.93 | HPRT1 (0.44) | HPRT1PDE3AMEN1KMT2ATK1 | |
| SCHEMBL710554 | 0.91 | MEN1 (0.43) | HPRT1PDE3AMEN1KMT2AMAPK1 | |
| SCHEMBL710555 | 0.91 | MEN1 (0.43) | HPRT1PDE3AMEN1KMT2AMAPK1 | |
| SCHEMBL712711 | 0.91 | HPRT1 (0.41) | HPRT1PDE3AMEN1KMT2AMAPK1 | |
| SCHEMBL712712 | 0.91 | HPRT1 (0.41) | HPRT1PDE3AMEN1KMT2AMAPK1 | |
| SCHEMBL8445893 | 0.90 | PDE3A (0.54) | HPRT1PDE3AMEN1KMT2AMAPK1 | |
| SCHEMBL5930142 | 0.86 | TK1 (0.53) | HPRT1MEN1KMT2ATK1PNP | |
| SCHEMBL8446041 | 0.86 | PDE3A (0.57) | HPRT1PDE3AMEN1KMT2AMAPK1 | |
| SCHEMBL8447893 | 0.86 | PDE3A (0.57) | HPRT1PDE3AMEN1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0942916-A2 | NUCLEOSIDES | Medivir Aktiebolag (SE) | 1999-09-22 | — | — | EP | disclosed |
| WO-1998021223-A1 | NUCLEOSIDES | MEDIVIR AB (SE) | 1998-05-22 | — | — | WO | disclosed |