⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19595403 | 0.85 | THRB (0.35) | — | |
| SCHEMBL12943459 | 0.72 | — | — | |
| SCHEMBL16660241 | 0.72 | — | — | |
| SCHEMBL13687380 | 0.72 | — | — | |
| SCHEMBL18665762 | 0.72 | — | — | |
| SCHEMBL23906711 | 0.72 | — | — | |
| SCHEMBL10015948 | 0.72 | — | — | |
| SCHEMBL8232415 | 0.72 | — | — | |
| SCHEMBL8050408 | 0.70 | — | — | |
| SCHEMBL16878868 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0909270-A4 | — | — | 1999-04-21 | — | — | EP | disclosed |
| EP-0909270-A1 | PROCESS FOR PREPARING 2,4-DIHYDROXYPYRIDINE AND 2,4-DIHYDROXY-3-NITROPYRIDINE | RHONE-POULENC RORER PHARMACEUTICALS, INC. (US) | 1999-04-21 | — | — | EP | disclosed |
| WO-1997024327-A1 | PROCESS FOR PREPARING 2,4-DIHYDROXYPYRIDINE AND 2,4-DIHYDROXY-3-NITROPYRIDINE | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1997-07-10 | — | — | WO | disclosed |