SCHEMBL8445975

SCHEMBL8445975

CCCCCCCCCc1ccccc1OC(C)OC(C)O

nearest known ligand 0.49

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
THRA P10827 1/20 0.49
THRB P10828 1/20 0.49
LIPG Q9Y5X9 1/20 0.46
ALOX5 P09917 1/20 0.46
PTGS2 P35354 1/20 0.46
ADRB2 P07550 5/20 0.45
ADRB1 P08588 5/20 0.45
PPARA Q07869 2/20 0.44
PPARG P37231 1/20 0.42
CYSLTR2 Q9NS75 4/20 0.40
CYSLTR1 Q9Y271 4/20 0.40
HTR1A P08908 1/20 0.38
ADRA2A P08913 1/20 0.38
ADRA2B P18089 1/20 0.38
ADRA2C P18825 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL330345 1.00 THRA (0.49) THRATHRBLIPGALOX5PTGS2
SCHEMBL21989 0.88 THRA (0.54) THRATHRBLIPGALOX5PTGS2
SCHEMBL28552517 0.88 THRA (0.54) THRATHRBLIPGALOX5PTGS2
SCHEMBL382121 0.88 THRA (0.54) THRATHRBLIPGALOX5PTGS2
Ammonia Solution, Strong SCHEMBL11585182 0.87 THRA (0.52) THRATHRBLIPGALOX5PTGS2
SCHEMBL11497857 0.86 THRA (0.47) THRATHRBLIPGALOX5PTGS2
SCHEMBL7650228 0.86 THRA (0.49) THRATHRBLIPGALOX5PTGS2
Hydrochloric Acid SCHEMBL11128855 0.83 THRA (0.44) THRATHRBLIPGALOX5PTGS2
SCHEMBL11265689 0.83 THRA (0.47) THRATHRBLIPGALOX5PTGS2
SCHEMBL9407233 0.83 THRA (0.44) THRATHRBLIPGALOX5PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2981752-B2 1999-11-22 JP claimed
JP-2981770-B2 1999-11-22 JP claimed
US-5972122-A USED IN ZERO-MERCURY, ZINC AIR ELECTROCHEMICAL CELL; INVOLVES CONTACTING ANODE CUP WITH AQUEOUS DETERSIVE SYSTEM CONTAINING ONE OR MORE SURFACTANTS AND SUBJECTED TO ULTRASONIC FIELD EVEREADY BATTERY COMPANY, INC. (US) 1999-10-26 US claimed
US-5397397-A Method for cleaning and drying of metallic and nonmetallic surfaces CRESTEK, INC. (US) 1995-03-14 US claimed
US-5395570-A Hollow fibre membrane extrusion MEMTEC LIMITED (AU) 1995-03-07 US claimed
EP-0408688-B1 POROUS MEMBRANES MEMTEC LTD (AU) 1994-03-23 EP claimed
US-5277851-A Removing surfactant from polyolefin fiber MEMTEC LIMITED (AU) 1994-01-11 US claimed
EP-0423249-A4 EXTRUSION OF HOLLOW FIBRE MEMBRANES 1991-05-22 EP claimed
EP-0423249-A1 EXTRUSION OF HOLLOW FIBRE MEMBRANES. MEMTEC LTD (AU) 1991-04-24 EP claimed
EP-0408688-A4 POROUS MEMBRANES 1991-04-17 EP claimed
EP-0408688-A1 POROUS MEMBRANES. MEMTEC LTD (AU) 1991-01-23 EP claimed
WO-1990005007-A1 POROUS MEMBRANES MEMTEC LIMITED (AU) 1990-05-17 WO claimed
WO-1990005006-A1 EXTRUSION OF HOLLOW FIBRE MEMBRANES MEMTEC LIMITED (AU) 1990-05-17 WO claimed
US-5972122-A USED IN ZERO-MERCURY, ZINC AIR ELECTROCHEMICAL CELL; INVOLVES CONTACTING ANODE CUP WITH AQUEOUS DETERSIVE SYSTEM CONTAINING ONE OR MORE SURFACTANTS AND SUBJECTED TO ULTRASONIC FIELD EVEREADY BATTERY COMPANY, INC. (US) 1999-10-26 US disclosed
US-5854145-A Corrosion inhibitor solution applicator CORTEC CORPORATION (US) 1998-12-29 US disclosed
US-5844012-A Process and composition for improving the cure of water-blown molded polyurethane foam AIR PRODUCTS AND CHEMICALS, INC. (US) 1998-12-01 US disclosed
EP-0408688-A4 POROUS MEMBRANES 1991-04-17 EP disclosed
EP-0408688-A1 POROUS MEMBRANES. MEMTEC LTD (AU) 1991-01-23 EP disclosed
WO-1990005007-A1 POROUS MEMBRANES MEMTEC LIMITED (AU) 1990-05-17 WO disclosed
WO-1990005006-A1 EXTRUSION OF HOLLOW FIBRE MEMBRANES MEMTEC LIMITED (AU) 1990-05-17 WO disclosed