⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8446236 | 1.00 | — | — | |
| SCHEMBL9842434 | 1.00 | — | — | |
| SCHEMBL330795 | 0.89 | CDK5 (0.31) | — | |
| SCHEMBL7668284 | 0.83 | NR1I2 (0.37) | — | |
| SCHEMBL14048880 | 0.83 | NR1I2 (0.37) | — | |
| SCHEMBL331086 | 0.83 | NR1I2 (0.37) | — | |
| SCHEMBL14049050 | 0.83 | NR1I2 (0.37) | — | |
| SCHEMBL4980169 | 0.83 | NR1I2 (0.37) | — | |
| SCHEMBL6322977 | 0.77 | — | — | |
| SCHEMBL8109272 | 0.73 | L3MBTL1 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0434450-B1 | Therapeutic nucleosides | WELLCOME FOUND (GB) | 1999-07-07 | — | — | EP | disclosed |
| EP-0921121-A1 | Intermediates to therapeutic nucleosides | THE WELLCOME FOUNDATION LIMITED (GB) | 1999-06-09 | — | — | EP | disclosed |
| EP-0921114-A1 | Intermediates to therapeutic nucleosides | THE WELLCOME FOUNDATION LIMITED (GB) | 1999-06-09 | — | — | EP | disclosed |
| US-5089500-A | Viricides; hepatitis, aids | BURROUGHS WELLCOME CO. (US) | 1992-02-18 | — | — | US | disclosed |
| US-5087697-A | Aids, viricides | BURROUGHS WELLCOME CO. (US) | 1992-02-11 | — | — | US | disclosed |
| US-5034394-A | Therapeutic nucleosides | BURROUGHS WELLCOME CO. (US) | 1991-07-23 | — | — | US | disclosed |
| EP-0434450-A2 | Therapeutic nucleosides | THE WELLCOME FOUNDATION LIMITED (GB) | 1991-06-26 | — | — | EP | disclosed |