Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.57 |
| ▸ | CNR2 | P34972 | 1/20 | 0.57 |
| ▸ | AGTR2 | P50052 | 5/20 | 0.34 |
| ▸ | AGTR1 | P30556 | 4/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL844232 | 0.88 | CNR1 (0.69) | CNR1CNR2AGTR2AGTR1 | |
| SCHEMBL844370 | 0.85 | CNR1 (0.75) | CNR1CNR2 | |
| SCHEMBL844881 | 0.83 | CNR1 (0.69) | CNR1CNR2 | |
| SCHEMBL845014 | 0.83 | CNR1 (0.80) | CNR1CNR2 | |
| SCHEMBL844571 | 0.81 | CNR1 (0.79) | CNR1CNR2 | |
| SCHEMBL17694535 | 0.74 | CNR1 (0.79) | CNR1CNR2 | |
| SCHEMBL17692331 | 0.73 | CNR1 (0.90) | CNR1CNR2 | |
| SCHEMBL844334 | 0.73 | CNR1 (0.68) | CNR1CNR2 | |
| SCHEMBL844174 | 0.73 | CNR1 (0.87) | CNR1CNR2 | |
| SCHEMBL17692388 | 0.72 | CNR1 (0.86) | CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1472234-B1 | QUINAZOLINONE DERIVATIVES AND THEIR USE AS CB AGONISTS | NOVARTIS AG (CH) | 2012-03-28 | — | — | EP | claimed |