Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.80 |
| ▸ | CNR2 | P34972 | 1/20 | 0.80 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.31 |
| ▸ | PKMYT1 | Q99640 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL844370 | 0.95 | CNR1 (0.75) | CNR1CNR2 | |
| SCHEMBL844881 | 0.93 | CNR1 (0.69) | CNR1CNR2PIK3CD | |
| Sad448 SCHEMBL844484 | 0.89 | CNR1 (1.00) | CNR1CNR2PIK3CDPKMYT1ALDH1A1 | |
| SCHEMBL17692388 | 0.87 | CNR1 (0.86) | CNR1CNR2PIK3CDPKMYT1ALDH1A1 | |
| SCHEMBL844333 | 0.85 | CNR1 (0.90) | CNR1CNR2PIK3CDPKMYT1 | |
| SCHEMBL17692331 | 0.84 | CNR1 (0.90) | CNR1CNR2PIK3CDALDH1A1KDM4E | |
| SCHEMBL18673206 | 0.83 | CNR1 (0.78) | CNR1CNR2PIK3CDALDH1A1KDM4E | |
| SCHEMBL844625 | 0.83 | CNR1 (0.57) | CNR1CNR2 | |
| SCHEMBL844174 | 0.82 | CNR1 (0.87) | CNR1CNR2PIK3CDALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL844735 | 0.81 | CNR1 (0.86) | CNR1CNR2PIK3CDALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1472234-B1 | QUINAZOLINONE DERIVATIVES AND THEIR USE AS CB AGONISTS | NOVARTIS AG (CH) | 2012-03-28 | — | — | EP | claimed |