Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL769209 | 0.83 | MEN1 (0.37) | MEN1KMT2AMAPK1L3MBTL1NLRP3 | |
| SCHEMBL9286903 | 0.80 | FFAR4 (0.32) | TSHR | |
| SCHEMBL769203 | 0.79 | MEN1 (0.32) | MEN1KMT2AMAPK1 | |
| SCHEMBL769315 | 0.77 | STS (0.36) | — | |
| SCHEMBL782117 | 0.74 | MEN1 (0.37) | MEN1KMT2AMAPK1L3MBTL1NLRP3 | |
| SCHEMBL9286737 | 0.73 | HDAC3 (0.34) | MEN1KMT2AMAPK1L3MBTL1NLRP3 | |
| SCHEMBL782276 | 0.73 | HDAC3 (0.35) | MEN1KMT2AMAPK1L3MBTL1NLRP3 | |
| SCHEMBL12505897 | 0.73 | MEN1 (0.34) | MEN1KMT2AMAPK1L3MBTL1NLRP3 | |
| SCHEMBL19139584 | 0.72 | KMT2A (0.34) | MEN1KMT2AMAPK1L3MBTL1ALDH1A1 | |
| SCHEMBL782509 | 0.72 | RAB9A (0.32) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2432785-B1 | HERBICIDAL SPIROHETEROCYCLIC TETRONIC ACID DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2014-10-15 | — | — | EP | disclosed |
| EP-2432785-A1 | HERBICIDAL SPIROHETEROCYCLIC TETRONIC ACID DERIVATIVES | Bayer CropScience AG (DE) | 2012-03-28 | — | — | EP | disclosed |
| WO-2010133337-A1 | HERBICIDAL SPIROHETEROCYCLIC TETRONIC ACID DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2010-11-25 | — | — | WO | disclosed |