Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 4/20 | 0.45 |
| ▸ | ACE | P12821 | 2/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.37 |
| ▸ | CTSD | P07339 | 7/20 | 0.37 |
| ▸ | MMEL1 | Q495T6 | 1/20 | 0.36 |
| ▸ | UTS2R | Q9UKP6 | 2/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8446449 | 0.92 | MME (0.47) | MMEACECTSBPPARGPPARA | |
| SCHEMBL8453149 | 0.90 | MME (0.47) | MMEACECTSBCYP26A1UTS2R | |
| SCHEMBL8452849 | 0.89 | ACE (0.45) | MMEACECTSBPPARGPPARD | |
| SCHEMBL8450108 | 0.84 | MME (0.45) | MMEACECTSBUTS2R | |
| SCHEMBL7568461 | 0.82 | MME (0.67) | MMEACE | |
| SCHEMBL8446426 | 0.80 | MME (0.48) | MMEACECTSBMMEL1LTA4H | |
| SCHEMBL8446488 | 0.79 | MME (0.56) | MMEACECTSB | |
| SCHEMBL8451198 | 0.78 | MME (0.48) | MMEACECTSB | |
| SCHEMBL8452068 | 0.78 | MME (0.48) | MMEACECTSB | |
| SCHEMBL8446482 | 0.78 | MME (0.49) | MMEACECTSBUTS2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5968980-A | ENDOPEPTIDASE 24.11 INHIBITORS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1999-10-19 | — | — | US | disclosed |