Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 4/20 | 0.45 |
| ▸ | ACE | P12821 | 3/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.39 |
| ▸ | UTS2R | Q9UKP6 | 6/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | CCKBR | P32239 | 1/20 | 0.36 |
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8453149 | 0.93 | MME (0.47) | MMEACECTSBUTS2RPTPN1 | |
| SCHEMBL8451198 | 0.92 | MME (0.48) | MMEACECTSBACACB | |
| SCHEMBL8450121 | 0.88 | CTSB (0.45) | MMEACECTSBCCKBR | |
| SCHEMBL8447081 | 0.87 | PPARG (0.42) | MMEACECTSBPTPN1CASP1 | |
| SCHEMBL8446449 | 0.86 | MME (0.47) | MMEACECTSBUTS2R | |
| SCHEMBL7567870 | 0.86 | MME (0.61) | MMEACECTSBHDAC1HDAC6 | |
| SCHEMBL8450113 | 0.86 | MME (0.43) | MMEACECTSBHDAC1HDAC6 | |
| SCHEMBL8446426 | 0.85 | MME (0.48) | MMEACECTSB | |
| SCHEMBL8452068 | 0.85 | MME (0.48) | MMEACECTSBACACB | |
| SCHEMBL8450105 | 0.85 | MME (0.54) | MMEACECTSBHDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5968980-A | ENDOPEPTIDASE 24.11 INHIBITORS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1999-10-19 | — | — | US | disclosed |