Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 12/20 | 0.53 |
| ▸ | ADORA3 | P0DMS8 | 10/20 | 0.53 |
| ▸ | ADORA2B | P29275 | 9/20 | 0.53 |
| ▸ | ADORA1 | P30542 | 8/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7223578 | 1.00 | ADORA2A (0.53) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL7229565 | 0.93 | ADORA2A (0.63) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL7221847 | 0.92 | ADORA2A (0.58) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL7459235 | 0.91 | ADORA2A (0.64) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL7513719 | 0.91 | ADORA2A (0.64) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL7513727 | 0.91 | ADORA2A (0.64) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL7231164 | 0.88 | ADORA2A (0.54) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL7456402 | 0.88 | ADORA2A (0.68) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL7230915 | 0.88 | ADORA2A (0.68) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL7232092 | 0.86 | ADORA3 (0.51) | ADORA2AADORA3ADORA2BADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0948509-A1 | 2-(PURIN-9-YL)-TETRAHYDROFURAN-3,4-DIOL DERIVATIVES | GLAXO GROUP LIMITED (GB) | 1999-10-13 | — | — | EP | disclosed |
| WO-1998028319-A1 | 2-(PURIN-9-YL)-TETRAHYDROFURAN-3,4-DIOL DERIVATIVES | GLAXO GROUP LIMITED (GB) | 1998-07-02 | — | — | WO | disclosed |