SCHEMBL844666

SCHEMBL844666

C=C(C)C(=O)OCC(CC(=C)C(=O)OC)OC(=O)C(=C)C

nearest known ligand 0.49

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.49
ALDH1A1 P00352 2/20 0.44
THRB P10828 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methacrylic Acid SCHEMBL4055237 0.95 TSHR (0.45) TSHRALDH1A1THRB
Acrylic Acid SCHEMBL6259608 0.92 TSHR (0.41) TSHRALDH1A1THRB
SCHEMBL6114867 0.86 KMT2A (0.38) TSHRALDH1A1
SCHEMBL7911797 0.86 TSHR (0.47) TSHRALDH1A1THRB
SCHEMBL248094 0.85 TSHR (0.50) TSHRALDH1A1THRB
Styrene SCHEMBL6115093 0.84 TSHR (0.35) TSHRALDH1A1
Methacrylic Acid SCHEMBL1561904 0.84 TSHR (0.49) TSHRALDH1A1THRB
SCHEMBL6523772 0.83 TSHR (0.45) TSHRALDH1A1THRB
SCHEMBL10938501 0.83 TSHR (0.45) TSHRALDH1A1THRB
SCHEMBL11058945 0.83 TSHR (0.45) TSHRALDH1A1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 355 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117752565-A Acne-removing essence and preparation method thereof 广州她她生物科技有限公司 2024-03-26 CN claimed
CN-116983227-A Hydroxy pinacolone retinoic acid ester composition and application thereof in skin care products 海南中和美业科技有限公司 2023-11-03 CN claimed
CN-116251035-A Oily composition containing retinol and/or retinol derivatives 深圳市护家科技有限公司 2023-06-13 CN claimed
CN-116099464-A Magnetic fluorescent microsphere and preparation method thereof 深圳海思安生物技术有限公司 2023-05-12 CN claimed
CN-114164483-B Preparation method of microbubble-driven photonic pigment 大连理工大学 2022-09-09 CN claimed
CN-114164483-A Preparation method of microbubble-driven photonic pigment 大连理工大学 2022-03-11 CN claimed
EP-3820448-A2 TOPICAL DETOMIDINE FORMULATIONS Clexio Biosciences Ltd. (IL) 2021-05-19 EP claimed
US-20210137830-A1 TOPICAL DETOMIDINE FORMULATIONS CLEXIO BIOSCIENCES LTD. (IL) 2021-05-13 US claimed
EP-2945706-B1 SOFT SOLID COSMETIC COMPOSITION COMPRISING ANIONIC SURFACTANTS AND POLYMERIC CONDITIONING AGENTS, AND COSMETIC TREATMENT METHOD OREAL (FR) 2021-01-06 EP claimed
CN-110974709-A Anti-acne composition 拉芳家化股份有限公司 2020-04-10 CN claimed
US-20020165198-A1 Fluorouracil-containing formulation BAUSCH HEALTH IRELAND LIMITED (IE) 2002-11-07 US claimed
WO-2001085102-A2 OIL-IN-WATER EMULSION FORMULATION CONTAINING HYDROQUINONE AND RETINOL R.P. SCHERER TECHNOLOGIES, INC. (US) 2001-11-15 WO claimed
EP-0876142-B1 TOPICAL DELIVERY OF DRUGS TO THE LOWER GASTROINTESTINAL TRACT ADVANCED POLYMER SYSTEMS INC (US) 2001-09-26 EP claimed
US-5874091-A PROTECTION OF SKIN AND HAIR AGAINST ULTRAVIOLET RADIATION AND FOR PIGMENTATION OF THE SKIN AND HAIR; HOMOGENEOUS AQUEOUS DISPERSION OF LAMELLAR AND ENCAPSULATING VESICLES; STORAGE STABILITY; STORING MELANIN PIGMENT IN THE STRATUM CORNEUM. L'OREAL (FR) 1999-02-23 US claimed
US-5849327-A Delivery of drugs to the lower gastrointestinal tract ADVANCED POLYMER SYSTEMS, INC. (US) 1998-12-15 US claimed
EP-0876142-A1 TOPICAL DELIVERY OF DRUGS TO THE LOWER GASTROINTESTINAL TRACT Advanced Polymer Systems, Inc. (US) 1998-11-11 EP claimed
WO-1997025980-A1 TOPICAL DELIVERY OF DRUGS TO THE LOWER GASTROINTESTINAL TRACT ADVANCED POLYMER SYSTEMS, INC. (US) 1997-07-24 WO claimed
EP-0575605-B1 MINERAL OR ORGANIC PARTICLE BASED PRODUCT COMPRISING AN INDOLINE PRODUCT OREAL (FR) 1996-11-27 EP claimed
EP-0313380-B1 Synthetic melanin aggregates ADVANCED POLYMER SYSTEMS INC (US) 1993-12-29 EP claimed
US-5145675-A Polymerizing suspended monomers in presence of porogen to form rigid crosslinked beads with internal pore network, extracting porogen, introducing active substance ADVANCED POLYMER SYSTEMS, INC. (US) 1992-09-08 US claimed