Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL844666 | 0.83 | TSHR (0.49) | TSHRTHRBALDH1A1 | |
| SCHEMBL10355752 | 0.83 | THRB (0.47) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL11751848 | 0.81 | THRB (0.45) | TSHRTHRB | |
| Methacrylic Acid SCHEMBL4055237 | 0.79 | TSHR (0.45) | TSHRTHRBALDH1A1 | |
| SCHEMBL17075267 | 0.77 | ALDH1A1 (0.56) | TSHRTHRBALDH1A1 | |
| SCHEMBL28343113 | 0.76 | TSHR (0.52) | TSHRTHRBALDH1A1 | |
| Acrylic Acid SCHEMBL6259608 | 0.76 | TSHR (0.41) | TSHRTHRBALDH1A1 | |
| SCHEMBL8162991 | 0.75 | TSHR (0.44) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL7545167 | 0.75 | THRB (0.52) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL2407775 | 0.75 | THRB (0.43) | TSHRTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1088848-B1 | Porous materials | SHIPLEY CO LLC (US) | 2005-12-28 | — | — | EP | disclosed |
| US-6602804-B2 | Dielectric, polymer blend | SHIPLEY COMPANY, L.L.C. | 2003-08-05 | — | — | US | disclosed |
| US-20030004218-A1 | Porous materials | SHIPLEY COMPANY, L.L.C. | 2003-01-02 | — | — | US | disclosed |
| US-6420441-B1 | DISPERSING REMOVABLE CROSSLINKED POLYMER POROGENS IN A POLYSILOXANE, CURING, AND HEATING TO REMOVE POROGEN; LOW DIELECTRIC CONSTANT; HIGH POROSITY; INSULATION MATERIALS | SHIPLEY COMPANY, L.L.C. | 2002-07-16 | — | — | US | disclosed |
| EP-1088848-A1 | Porous materials | Shipley Company LLC (US) | 2001-04-04 | — | — | EP | disclosed |