Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 4/20 | 0.44 |
| ▸ | ACE | P12821 | 4/20 | 0.44 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.37 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.37 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.35 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.34 |
| ▸ | ITGB7 | P26010 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.34 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.33 |
| ▸ | FPR2 | P25090 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8450803 | 0.89 | MME (0.48) | MMEACECTSBFDFT1PSMB5 | |
| SCHEMBL7573787 | 0.88 | MME (0.59) | MMEACELPAR1ITGA4ITGB7 | |
| SCHEMBL7573781 | 0.88 | MME (0.59) | MMEACELPAR1ITGA4ITGB7 | |
| SCHEMBL8449676 | 0.88 | MME (0.48) | MMEACECTSBFDFT1PSMB5 | |
| SCHEMBL8447092 | 0.87 | MME (0.45) | MMEACECTSBUSP2LPAR1 | |
| SCHEMBL8449331 | 0.86 | MME (0.44) | MMEACEUSP2LPAR1LPAR5 | |
| SCHEMBL8447085 | 0.85 | MME (0.51) | MMEACECTSBLPAR1LPAR5 | |
| SCHEMBL8451848 | 0.85 | MME (0.46) | MMEACECTSBUSP2LPAR1 | |
| SCHEMBL8446471 | 0.84 | MME (0.47) | MMEACECTSBFDFT1ACACB | |
| SCHEMBL8446405 | 0.84 | MME (0.48) | MMEACECTSBFDFT1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5968980-A | ENDOPEPTIDASE 24.11 INHIBITORS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1999-10-19 | — | — | US | disclosed |