Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 4/20 | 0.44 |
| ▸ | ACE | P12821 | 3/20 | 0.44 |
| ▸ | MMP3 | P08254 | 3/20 | 0.39 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 3/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.37 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8447092 | 0.95 | MME (0.45) | MMEACELPAR1USP2FDFT1 | |
| SCHEMBL8449483 | 0.91 | MME (0.42) | MMEACEMMP3LPAR1LPAR5 | |
| SCHEMBL8451246 | 0.88 | MME (0.47) | MMEACEMMP3FDFT1 | |
| SCHEMBL8450247 | 0.88 | MME (0.47) | MMEACEMMP3FDFT1 | |
| SCHEMBL7566362 | 0.88 | MME (0.59) | MMEACEMMP3LPAR1ALDH1A1 | |
| SCHEMBL7566370 | 0.88 | MME (0.59) | MMEACEMMP3LPAR1ALDH1A1 | |
| SCHEMBL8449905 | 0.87 | MME (0.52) | MMEACEMMP3FDFT1 | |
| SCHEMBL8451265 | 0.87 | MME (0.49) | MMEACEMMP3FDFT1 | |
| SCHEMBL8447086 | 0.86 | MME (0.44) | MMEACELPAR1USP2FDFT1 | |
| SCHEMBL8451848 | 0.85 | MME (0.46) | MMEACELPAR1USP2FDFT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5968980-A | ENDOPEPTIDASE 24.11 INHIBITORS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1999-10-19 | — | — | US | disclosed |