SCHEMBL8447126 — predicted protein targets

Predicted protein targets (top 14)

	gene	UniProt	supporting neighbours	confidence
▸	MME	P08473	6/20	0.46

▸	ACE	P12821	5/20	0.46

▸	MMEL1	Q495T6	1/20	0.40

▸	MEN1	O00255	1/20	0.38

▸	KMT2A	Q03164	1/20	0.38

▸	NLRP3	Q96P20	2/20	0.38

▸	TACR1	P25103	1/20	0.37

▸	PPARG	P37231	3/20	0.37

▸	PPARD	Q03181	2/20	0.37

▸	GPR34	Q9UPC5	2/20	0.37

▸	CTSB	P07858	1/20	0.37

▸	MBTPS1	Q14703	1/20	0.36

▸	POLB	P06746	1/20	0.36

▸	PPARA	Q07869	1/20	0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL8447130	0.95	MME (0.45)	MMEACEMMEL1MEN1KMT2A
SCHEMBL8450828	0.95	MME (0.47)	MMEACEMMEL1MEN1KMT2A
SCHEMBL8449727	0.93	MME (0.45)	MMEACEMMEL1NLRP3PPARG
SCHEMBL7566393	0.92	MME (0.55)	MMEACEMMEL1PPARGPPARD
SCHEMBL7566387	0.92	MME (0.55)	MMEACEMMEL1PPARGPPARD
SCHEMBL8449910	0.89	MME (0.46)	MMEACEMMEL1MEN1KMT2A
SCHEMBL8449499	0.89	MME (0.49)	MMEACETACR1CTSB
SCHEMBL7574128	0.89	MME (0.53)	MMEACEMMEL1PPARGPPARD
SCHEMBL7570073	0.89	MME (0.53)	MMEACEMMEL1PPARGPPARD
SCHEMBL7569417	0.88	MME (0.56)	MMEACEMMEL1PPARGPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-5968980-A	ENDOPEPTIDASE 24.11 INHIBITORS	SANTEN PHARMACEUTICAL CO., LTD. (JP)	1999-10-19	—	—	US	disclosed