Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 6/20 | 0.47 |
| ▸ | ACE | P12821 | 5/20 | 0.47 |
| ▸ | MMEL1 | Q495T6 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.39 |
| ▸ | TACR1 | P25103 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 3/20 | 0.38 |
| ▸ | PPARD | Q03181 | 2/20 | 0.38 |
| ▸ | GPR34 | Q9UPC5 | 2/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
| ▸ | MBTPS1 | Q14703 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8447126 | 0.95 | MME (0.46) | MMEACEMMEL1MEN1KMT2A | |
| SCHEMBL8447130 | 0.94 | MME (0.45) | MMEACEMMEL1MEN1KMT2A | |
| SCHEMBL7569408 | 0.93 | MME (0.56) | MMEACEMMEL1PPARGPPARD | |
| SCHEMBL7569417 | 0.93 | MME (0.56) | MMEACEMMEL1PPARGPPARD | |
| SCHEMBL8449727 | 0.91 | MME (0.45) | MMEACEMMEL1NLRP3PPARG | |
| SCHEMBL8449910 | 0.91 | MME (0.46) | MMEACEMMEL1MEN1KMT2A | |
| SCHEMBL8450134 | 0.89 | MMEL1 (0.48) | MMEACEMMEL1MEN1KMT2A | |
| SCHEMBL8451250 | 0.88 | MME (0.45) | MMEACEMMEL1NLRP3PPARG | |
| SCHEMBL7566387 | 0.87 | MME (0.55) | MMEACEMMEL1PPARGPPARD | |
| SCHEMBL7566393 | 0.87 | MME (0.55) | MMEACEMMEL1PPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5968980-A | ENDOPEPTIDASE 24.11 INHIBITORS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1999-10-19 | — | — | US | disclosed |