Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 8/20 | 0.50 |
| ▸ | ACE | P12821 | 7/20 | 0.50 |
| ▸ | CTSB | P07858 | 1/20 | 0.45 |
| ▸ | FDFT1 | P37268 | 2/20 | 0.41 |
| ▸ | PTGES | O14684 | 1/20 | 0.40 |
| ▸ | CASR | P41180 | 1/20 | 0.38 |
| ▸ | CPA1 | P15085 | 2/20 | 0.37 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.37 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.36 |
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
| ▸ | ACACA | Q13085 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8450012 | 0.93 | MME (0.49) | MMEACECTSBFDFT1PTGES | |
| SCHEMBL8446467 | 0.92 | MME (0.53) | MMEACECTSBFDFT1PTGES | |
| SCHEMBL8452068 | 0.92 | MME (0.48) | MMEACECTSBFDFT1PTGES | |
| SCHEMBL8451198 | 0.92 | MME (0.48) | MMEACECTSBFDFT1ACE2 | |
| SCHEMBL8446426 | 0.92 | MME (0.48) | MMEACECTSBFDFT1PTGES | |
| SCHEMBL8451848 | 0.91 | MME (0.46) | MMEACECTSBFDFT1LPAR1 | |
| SCHEMBL8447319 | 0.89 | MME (0.51) | MMEACECTSBFDFT1PTGES | |
| SCHEMBL8452849 | 0.88 | ACE (0.45) | MMEACECTSBFDFT1CPA1 | |
| SCHEMBL8451834 | 0.87 | MME (0.44) | MMEACECTSBFDFT1PTGES | |
| SCHEMBL8450149 | 0.86 | MME (0.43) | MMEACECTSBFDFT1ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5968980-A | ENDOPEPTIDASE 24.11 INHIBITORS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1999-10-19 | — | — | US | disclosed |