Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 4/20 | 0.43 |
| ▸ | ACE | P12821 | 3/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.36 |
| ▸ | ACACB | O00763 | 2/20 | 0.35 |
| ▸ | ACACA | Q13085 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8451848 | 0.88 | MME (0.46) | MMEACECTSBFDFT1 | |
| SCHEMBL7568446 | 0.86 | MME (0.59) | MMEACECTSBLMNARAB9A | |
| SCHEMBL8447157 | 0.86 | MME (0.50) | MMEACECTSBFDFT1ACACB | |
| SCHEMBL8450012 | 0.85 | MME (0.49) | MMEACECTSBFDFT1ACACB | |
| SCHEMBL8446467 | 0.84 | MME (0.53) | MMEACECTSBFDFT1 | |
| SCHEMBL8452068 | 0.84 | MME (0.48) | MMEACECTSBSMN1; SMN2FDFT1 | |
| SCHEMBL8446426 | 0.84 | MME (0.48) | MMEACECTSBFDFT1 | |
| SCHEMBL8451198 | 0.84 | MME (0.48) | MMEACECTSBRAB9AKMT2A | |
| SCHEMBL8451834 | 0.83 | MME (0.44) | MMEACECTSBRAB9ASMN1; SMN2 | |
| SCHEMBL8447319 | 0.81 | MME (0.51) | MMEACECTSBFDFT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5968980-A | ENDOPEPTIDASE 24.11 INHIBITORS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1999-10-19 | — | — | US | disclosed |