Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 7/20 | 0.60 |
| ▸ | CYP17A1 | P05093 | 7/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | PGR | P06401 | 1/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9596052 | 0.91 | CYP19A1 (0.53) | CYP19A1CYP17A1CYP3A4MEN1NR1I2 | |
| SCHEMBL14415947 | 0.78 | CYP19A1 (0.59) | CYP19A1CYP17A1CYP3A4CYP24A1CYP27B1 | |
| SCHEMBL11366789 | 0.76 | CYP19A1 (1.00) | CYP19A1CYP17A1CYP3A4MEN1NR1I2 | |
| SCHEMBL7276614 | 0.75 | CYP17A1 (0.61) | CYP19A1CYP17A1CYP3A4MEN1NR1I2 | |
| SCHEMBL27415471 | 0.73 | CYP19A1 (0.56) | CYP19A1CYP17A1CYP3A4CYP24A1CYP27B1 | |
| SCHEMBL11353276 | 0.72 | CYP19A1 (0.91) | CYP19A1CYP17A1CYP3A4MEN1NR1I2 | |
| SCHEMBL27484897 | 0.70 | CYP17A1 (0.63) | CYP19A1CYP17A1CYP3A4MEN1NR1I2 | |
| SCHEMBL11370543 | 0.70 | CYP19A1 (0.85) | CYP19A1CYP17A1CYP3A4MEN1NR1I2 | |
| SCHEMBL10693298 | 0.69 | CYP19A1 (1.00) | CYP19A1CYP17A1CYP3A4MEN1NR1I2 | |
| SCHEMBL7296537 | 0.69 | HRH1 (0.75) | CYP3A4MEN1MAPTIDO1CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0618907-B1 | 1-(ARYLALKYL-AMINOALKYL)IMIDAZOLE DERIVATIVES, PROCESSES OF PREPARATION AND USE AS THERAPEUTICAL AGENTS | BRITISH TECH GROUP INT (GB) | 1999-04-28 | — | — | EP | disclosed |
| WO-1995022327-A1 | USE OF 1-(ARYLALKYLAMINOALKYL) IMIDAZOLES FOR TREATING NEUROLOGICAL DAMAGE | KNOLL AG (DE) | 1995-08-24 | — | — | WO | disclosed |