Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 5/20 | 0.59 |
| ▸ | CYP17A1 | P05093 | 11/20 | 0.53 |
| ▸ | CYP24A1 | Q07973 | 4/20 | 0.49 |
| ▸ | CYP27B1 | O15528 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27415471 | 0.91 | CYP19A1 (0.56) | CYP19A1CYP17A1CYP24A1CYP27B1CYP3A4 | |
| SCHEMBL7276614 | 0.84 | CYP17A1 (0.61) | CYP19A1CYP17A1CYP24A1CYP27B1CYP3A4 | |
| SCHEMBL8973344 | 0.82 | CYP17A1 (0.71) | CYP19A1CYP17A1CYP3A4 | |
| SCHEMBL8149595 | 0.81 | CYP19A1 (0.66) | CYP19A1CYP17A1 | |
| SCHEMBL8447209 | 0.78 | CYP19A1 (0.60) | CYP19A1CYP17A1CYP24A1CYP27B1CYP3A4 | |
| SCHEMBL27569078 | 0.78 | CYP17A1 (0.54) | CYP19A1CYP17A1 | |
| Hydrochloric Acid SCHEMBL3649216 | 0.77 | CYP19A1 (0.56) | CYP19A1CYP17A1CYP24A1CYP27B1CYP3A4 | |
| SCHEMBL27365603 | 0.77 | CYP17A1 (0.65) | CYP19A1CYP17A1CYP24A1 | |
| SCHEMBL27484897 | 0.76 | CYP17A1 (0.63) | CYP19A1CYP17A1CYP24A1CYP3A4 | |
| SCHEMBL9201425 | 0.75 | CYP19A1 (0.55) | CYP19A1CYP17A1CYP24A1CYP27B1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070213340-A1 | Farnesyl protein transferase inhibitors | SCHERING CORPORATION | 2007-09-13 | — | — | US | disclosed |
| US-20070213340-A1 | Farnesyl protein transferase inhibitors | SCHERING CORPORATION | 2007-09-13 | — | — | US | disclosed |
| WO-2007084498-A1 | PIPERAZINE DERIVATIVES AS FARNESYL PROTEIN TRANSFERASE INHIBITORS | SCHERING CORPORATION (US) | 2007-07-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070213340-A1 | Farnesyl protein transferase inhibitors | FNTB, FNTA, FDPS | CYP19A1 1629/4885CYP17A1 1497/4885CYP24A1 2311/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.