Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 1/20 | 0.57 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.57 |
| ▸ | HTR5A | P47898 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 4/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | CASP6 | P55212 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30242138 | 1.00 | PDK2 (0.57) | PDK2PDK4HTR5AKMT2AMEN1 | |
| SCHEMBL31911 | 0.80 | PDK2 (0.67) | PDK2PDK4HTR5AKMT2AMEN1 | |
| SCHEMBL29371027 | 0.80 | PDK2 (0.67) | PDK2PDK4HTR5AKMT2AMEN1 | |
| SCHEMBL20686392 | 0.78 | PDK2 (0.53) | PDK2PDK4HTR5AKMT2AMEN1 | |
| SCHEMBL28706253 | 0.78 | PDK2 (0.64) | PDK2PDK4HTR5AKMT2AMEN1 | |
| SCHEMBL12723263 | 0.73 | PDK2 (0.57) | PDK2PDK4HTR5AKMT2AMEN1 | |
| SCHEMBL11981398 | 0.73 | PDK2 (0.57) | PDK2PDK4HTR5AKMT2AMEN1 | |
| SCHEMBL319934 | 0.73 | PDK2 (1.00) | PDK2PDK4KMT2AMEN1GAA | |
| SCHEMBL29518706 | 0.73 | PDK2 (1.00) | PDK2PDK4KMT2AMEN1GAA | |
| Boric Acid SCHEMBL28431171 | 0.73 | PDK2 (0.57) | PDK2PDK4HTR5AKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109721616-A | Quino spirooxazine class photochromic compound and preparation method thereof | 天津孚信阳光科技有限公司 | 2019-05-07 | — | — | CN | claimed |
| CN-106833007-B | A kind of environment-friendly preparation method of orange 107 dyestuffs of solvent | 安徽清科瑞洁新材料有限公司 | 2018-12-11 | — | — | CN | claimed |
| CN-104892631-B | Class photochromic compound of spirooxazine containing sulfonic group and its preparation method and application | 中国中化股份有限公司 | 2018-03-02 | — | — | CN | claimed |
| CN-106833007-A | A kind of environment-friendly preparation method of 107 dyestuffs of solvent orange | 安徽清科瑞洁新材料有限公司 | 2017-06-13 | — | — | CN | claimed |
| CN-118324686-A | Diazacyclo compound, cyclic trimethylcyanine compound, preparation methods thereof, imaging agent and application | 南京大学 | 2024-07-12 | — | — | CN | disclosed |
| EP-3309552-B1 | DYE COMPOUND | SFC CO LTD (KR) | 2024-01-17 | — | — | EP | disclosed |
| WO-2020060937-A1 | NARROW ABSORPTION POLYMER NANOPARTICLES AND RELATED METHODS | UNIVERSITY OF WASHINGTON (US) | 2020-03-26 | — | — | WO | disclosed |
| US-20200087305-A1 | SUBSTITUTED HETEROCYCLE FUSED GAMMA-CARBOLINES SYNTHESIS | INTRA-CELLULAR THERAPIES, INC. (US) | 2020-03-19 | — | — | US | disclosed |
| CN-106833007-B | A kind of environment-friendly preparation method of orange 107 dyestuffs of solvent | 安徽清科瑞洁新材料有限公司 | 2018-12-11 | — | — | CN | disclosed |
| CN-106833007-B | A kind of environment-friendly preparation method of orange 107 dyestuffs of solvent | 安徽清科瑞洁新材料有限公司 | 2018-12-11 | — | — | CN | disclosed |
| EP-2999704-B1 | SPIRO[CHROMAN-2,2'-INDOLE]DERIVATIVES AS CYANIDE ION CHEMOSENSORS | KAUNAS UNIV OF TECHNOLOGY (LT) | 2018-10-10 | — | — | EP | disclosed |
| CN-105175431-B | Bifunctional photochromic compound, synthesis and application thereof | 南京工业大学 | 2018-03-30 | — | — | CN | disclosed |
| US-5288592-A | Transition metal-spirobenzopyran complex, a production process therefor and a photochromic material comprising the complex | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1994-02-22 | — | — | US | disclosed |
| US-5252742-A | Spiropyran compounds | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1993-10-12 | — | — | US | disclosed |
| US-5241027-A | MACROMOLECULAR SPIROPYRAN COMPOUNDS | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1993-08-31 | — | — | US | disclosed |
| EP-0530369-A1 | CRYSTAL COMPRISING INDOLINOSPIROBENZOTHIOPYRAN DERIVATIVE AND RING-OPENING ISOMER THEREOF | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1993-03-10 | — | — | EP | disclosed |
| EP-0530371-A1 | TRANSITION METAL-SPIROBENZOPYRAN COMPLEX, PRODUCTION THEREOF, AND PHOTOCHROMIC MATERIAL COMPRISING THE SAME | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1993-03-10 | — | — | EP | disclosed |
| EP-0529100-A1 | INDOLINOSPIROBENZOPYRAN DERIVATIVE | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1993-03-03 | — | — | EP | disclosed |
| EP-0466938-A1 | HIGH-MOLECULAR SPIROPYRAN COMPOUND | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1992-01-22 | — | — | EP | disclosed |
| EP-0411157-A1 | SPIROPYRAN COMPOUNDS | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1991-02-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200087305-A1 | SUBSTITUTED HETEROCYCLE FUSED GAMMA-CARBOLINES SYNTHESIS | HCCS, CYCS, CBR3 | PDK2 392/4885PDK4 590/4885HTR5A 1095/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.