Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 5/20 | 0.48 |
| ▸ | ACE | P12821 | 5/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.37 |
| ▸ | ITGAV | P06756 | 2/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | CTSA | P10619 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8448381 | 0.87 | MME (0.52) | MMEACEHPGDCASP1ITGB3 | |
| SCHEMBL8452362 | 0.85 | MME (0.51) | MMEACEEPHX2CASP1ITGB3 | |
| SCHEMBL8452955 | 0.85 | MME (0.64) | MMEACEHPGDEPHX2CASP1 | |
| SCHEMBL8452949 | 0.83 | MME (0.54) | MMEACEHPGDALDH1A1EPHX2 | |
| SCHEMBL8452837 | 0.82 | MME (0.53) | MMEACEHPGDEPHX2ITGB3 | |
| SCHEMBL8027076 | 0.81 | MME (0.74) | MMEACEHPGDKDM4EALDH1A1 | |
| SCHEMBL8448709 | 0.81 | MME (0.48) | MMEACEITGB3ITGAVCTSA | |
| SCHEMBL8027498 | 0.78 | MME (0.75) | MMEACEHPGDKDM4EALDH1A1 | |
| SCHEMBL8447752 | 0.77 | MME (0.44) | MMEACEALDH1A1CASP1ITGB3 | |
| SCHEMBL8017309 | 0.77 | MME (0.59) | MMEACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5891912-A | ENDOPEPTIDASE 24.11 INHIBITORS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1999-04-06 | — | — | US | disclosed |