Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 5/20 | 0.51 |
| ▸ | ACE | P12821 | 5/20 | 0.51 |
| ▸ | CASP1 | P29466 | 6/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.40 |
| ▸ | ITGAV | P06756 | 2/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | METAP2 | P50579 | 1/20 | 0.39 |
| ▸ | METAP1 | P53582 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8448381 | 0.90 | MME (0.52) | MMEACECASP1ITGB3ITGAV | |
| SCHEMBL8452955 | 0.88 | MME (0.64) | MMEACECASP1EPHX2ITGB3 | |
| SCHEMBL8454342 | 0.88 | CASP1 (0.50) | CASP1EPHX2ITGB3ITGAVCTSB | |
| SCHEMBL8447813 | 0.87 | CASP1 (0.49) | CASP1EPHX2ITGB3ITGAVMETAP2 | |
| SCHEMBL8454177 | 0.87 | MME (0.43) | MMEACECTSB | |
| SCHEMBL8452949 | 0.86 | MME (0.54) | MMEACECASP1EPHX2ITGB3 | |
| SCHEMBL8447554 | 0.85 | MME (0.48) | MMEACECASP1EPHX2ITGB3 | |
| SCHEMBL8452837 | 0.85 | MME (0.53) | MMEACEEPHX2ITGB3ITGAV | |
| SCHEMBL8447608 | 0.85 | MME (0.47) | MMEACECASP1CTSB | |
| SCHEMBL8448709 | 0.84 | MME (0.48) | MMEACEITGB3ITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5891912-A | ENDOPEPTIDASE 24.11 INHIBITORS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1999-04-06 | — | — | US | disclosed |