Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.46 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.38 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8444195 | 0.76 | HCAR2 (0.39) | HCAR2 | |
| Acetic Acid SCHEMBL27784249 | 0.74 | HCAR2 (0.61) | HCAR2MKNK1MKNK2 | |
| SCHEMBL7958559 | 0.73 | — | — | |
| SCHEMBL1651203 | 0.69 | HCAR2 (0.67) | HCAR2MKNK1MKNK2 | |
| SCHEMBL29111879 | 0.69 | HCAR2 (0.60) | HCAR2MKNK1MKNK2CHRNB2CHRNA4 | |
| SCHEMBL3372685 | 0.69 | HCAR2 (0.46) | HCAR2MKNK1MKNK2 | |
| SCHEMBL3644220 | 0.69 | CYP2C19 (0.43) | — | |
| SCHEMBL30955683 | 0.66 | HCAR2 (0.42) | HCAR2MKNK1MKNK2 | |
| SCHEMBL19778529 | 0.65 | HCAR2 (0.46) | HCAR2MKNK1MKNK2 | |
| SCHEMBL8447661 | 0.65 | RIPK1 (0.47) | HCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0901490-A1 | BICYCLIC AMINES AS INSECTICIDES | ZENECA LIMITED (GB) | 1999-03-17 | — | — | EP | disclosed |
| WO-1997043286-A1 | BICYCLIC AMINES AS INSECTICIDES | ZENECA LIMITED (GB) | 1997-11-20 | — | — | WO | disclosed |