Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | DNM1 | Q05193 | 7/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11661753 | 1.00 | TSHR (0.53) | TSHRTHRBALDH1A1DNM1LMNA | |
| SCHEMBL6107195 | 1.00 | TSHR (0.53) | TSHRTHRBALDH1A1DNM1LMNA | |
| SCHEMBL119677 | 1.00 | TSHR (0.53) | TSHRTHRBALDH1A1DNM1LMNA | |
| SCHEMBL11690578 | 1.00 | TSHR (0.53) | TSHRTHRBALDH1A1DNM1LMNA | |
| SCHEMBL3277853 | 1.00 | TSHR (0.53) | TSHRTHRBALDH1A1DNM1LMNA | |
| SCHEMBL305825 | 1.00 | TSHR (0.53) | TSHRTHRBALDH1A1DNM1LMNA | |
| SCHEMBL10318693 | 1.00 | TSHR (0.53) | TSHRTHRBALDH1A1DNM1LMNA | |
| SCHEMBL699509 | 1.00 | — | — | |
| SCHEMBL146783 | 1.00 | — | — | |
| SCHEMBL31181884 | 1.00 | TSHR (0.53) | TSHRTHRBALDH1A1DNM1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118878395-A | 1-Halo-2,6,14-trimethyloctadecane compound and process for preparing 5,13,17-trimethylalkane compound therefrom | 信越化学工业株式会社 | 2024-11-01 | — | — | CN | disclosed |
| US-5856326-A | ANTITUMOR, ANTICANCER AGENTS | MERCK & CO., INC. (US) | 1999-01-05 | — | — | US | disclosed |
| EP-0820445-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | Merck & Co., Inc. (US) | 1998-01-28 | — | — | EP | disclosed |
| WO-1996030343-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 1996-10-03 | — | — | WO | disclosed |