SCHEMBL119677

SCHEMBL119677

CCCCCCCCCCCCCCCCCC[Mg]Cl

nearest known ligand 0.53

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.53
THRB P10828 1/20 0.53
ALDH1A1 P00352 3/20 0.47
DNM1 Q05193 7/20 0.40
LMNA P02545 2/20 0.40
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
HSD17B10 Q99714 1/20 0.40
SLC22A1 O15245 1/20 0.40
EPHX1 P07099 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11661753 1.00 TSHR (0.53) TSHRTHRBALDH1A1DNM1LMNA
SCHEMBL6107195 1.00 TSHR (0.53) TSHRTHRBALDH1A1DNM1LMNA
SCHEMBL11690578 1.00 TSHR (0.53) TSHRTHRBALDH1A1DNM1LMNA
SCHEMBL3277853 1.00 TSHR (0.53) TSHRTHRBALDH1A1DNM1LMNA
SCHEMBL305825 1.00 TSHR (0.53) TSHRTHRBALDH1A1DNM1LMNA
SCHEMBL10318693 1.00 TSHR (0.53) TSHRTHRBALDH1A1DNM1LMNA
SCHEMBL699509 1.00
SCHEMBL8447776 1.00 TSHR (0.53) TSHRTHRBALDH1A1DNM1LMNA
SCHEMBL146783 1.00
SCHEMBL31181884 1.00 TSHR (0.53) TSHRTHRBALDH1A1DNM1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 144 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025242747-A1 MULTI -COMPONENT FORMULATIONS OF ORGANOMETALLIC REAGENTS MERCK PATENT GMBH (DE) 2025-11-27 WO claimed
CN-119059795-B Preparation method of phenolic aerogel composite heat insulation tile 山东工业陶瓷研究设计院有限公司 2025-01-21 CN claimed
CN-119191865-A Short fiber carbon ceramic composite material brake disc and preparation method thereof 山东旌丞新材料科技有限公司 2024-12-27 CN claimed
CN-119059795-A Preparation method of phenolic aerogel composite heat insulation tile 山东工业陶瓷研究设计院有限公司 2024-12-03 CN claimed
CN-118561305-B High-heat-conductivity high-purity spherical magnesium oxide precursor and preparation method thereof 山东工业陶瓷研究设计院有限公司 2024-10-22 CN claimed
CN-118561303-B Low-cost high-purity high-densification spherical magnesia powder and preparation method thereof 山东工业陶瓷研究设计院有限公司 2024-10-22 CN claimed
CN-118561305-A High-heat-conductivity high-purity spherical magnesium oxide precursor and preparation method thereof 山东工业陶瓷研究设计院有限公司 2024-08-30 CN claimed
CN-118561303-A Low-cost high-purity high-densification spherical magnesia powder and preparation method thereof 山东工业陶瓷研究设计院有限公司 2024-08-30 CN claimed
CN-113403150-B Method for cleaning, killing and killing air-conditioning pipeline of cigarette factory 河南省紫风养护发展有限公司 2022-07-05 CN claimed
CN-113403150-A Method for cleaning, eliminating and killing air-conditioning pipeline of cigarette factory 河南省紫风养护发展有限公司 2021-09-17 CN claimed
US-7273948-B2 Process of preparing esters and ethers of probucol and derivatives thereof ATHEROGENICS, INC. (US) 2007-09-25 US claimed
EP-1594824-A4 PROCESS OF PREPARING ESTERS AND ETHERS OF PROBUCOL AND DERIVATIVES THEREOF ATHEROGENICS INC (US) 2007-04-04 EP claimed
EP-1594824-A2 PROCESS OF PREPARING ESTERS AND ETHERS OF PROBUCOL AND DERIVATIVES THEREOF Atherogenics, Inc. (US) 2005-11-16 EP claimed
US-20040204485-A1 Process of preparing esters and ethers of probucol and derivatives thereof CRABTREE ACQUISITION CO, LLC 2004-10-14 US claimed
WO-2004062622-A2 PROCESS OF PREPARING ESTERS AND ETHERS OF PROBUCOL AND DERIVATIVES THEREOF ATHEROGENICS, INC. (US) 2004-07-29 WO claimed
WO-2025242747-A1 MULTI -COMPONENT FORMULATIONS OF ORGANOMETALLIC REAGENTS MERCK PATENT GMBH (DE) 2025-11-27 WO disclosed
US-20250312287-A1 LIPID NANOPARTICLES COMPRISING AN IMIDAZOLIUM-BASED CATIONIC LIPID POLYPLUS TRANSFECTION (FR) 2025-10-09 US disclosed
US-5414133-A Protected phosphine oxides CIBA-GEIGY CORPORATION (US) 1995-05-09 US disclosed
US-5298663-A Process for the preparation of protected phosphine oxides CIBA-GEIGY CORPORATION (US) 1994-03-29 US disclosed
EP-0501702-A2 Process for the preparation of protected phosphine oxides CIBA-GEIGY AG (CH) 1992-09-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250312287-A1 LIPID NANOPARTICLES COMPRISING AN IMIDAZOLIUM-BASED CATIONIC LIPID NPC1L1, CETP, LNPK TSHR 486/4885THRB 1110/4885ALDH1A1 4418/4885
US-20040204485-A1 Process of preparing esters and ethers of probucol and derivatives thereof NR3C2, MGLL, GCG TSHR 1000/4885THRB 269/4885ALDH1A1 2574/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.