SCHEMBL84479

SCHEMBL84479

O=C1OC(=O)c2cc(Sc3ccccc3)ccc21

nearest known ligand 0.66

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAOA P21397 7/20 0.66
MAOB P27338 7/20 0.66
BCL2 P10415 4/20 0.57
MCL1 Q07820 4/20 0.57
ALOX15 P16050 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
ALDH1A1 P00352 2/20 0.42
HPGD P15428 1/20 0.40
CA12 O43570 1/20 0.38
CA1 P00915 1/20 0.38
CA4 P22748 1/20 0.38
CA7 P43166 1/20 0.38
KDM4E B2RXH2 1/20 0.37
NSD2 O96028 1/20 0.37
MAPT P10636 1/20 0.37
MAPK1 P28482 1/20 0.37
HTR2C P28335 1/20 0.37
HTR6 P50406 1/20 0.37
PTGS2 P35354 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13298544 0.94 MAOA (0.56) MAOAMAOBBCL2MCL1ALOX15
SCHEMBL92584 0.94 MAOA (0.56) MAOAMAOBBCL2MCL1ALOX15
SCHEMBL29383846 0.92 MAOA (0.53) MAOAMAOBBCL2MCL1ALOX15
SCHEMBL301318 0.92 MAOA (0.53) MAOAMAOBBCL2MCL1ALOX15
SCHEMBL84478 0.90 MAOA (0.53) MAOAMAOBBCL2MCL1ALOX15
SCHEMBL19034747 0.90 MAOA (0.53) MAOAMAOBBCL2MCL1ALOX15
SCHEMBL15119599 0.85 MAOA (0.53) MAOAMAOBBCL2MCL1ALOX15
SCHEMBL9329811 0.84 MAOA (0.49) MAOAMAOBBCL2MCL1ALDH1A1
SCHEMBL24946582 0.84 MAOA (0.47) MAOAMAOBBCL2MCL1ALOX15
SCHEMBL15695588 0.82 MAOA (0.46) MAOAMAOBBCL2MCL1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2617578-B1 HEAT-SENSITIVE CHROMOGENIC COMPOSITION AND HEAT-SENSITIVE RECORDING MATERIAL FORMED USING SAID COMPOSITION YAMAMOTO CHEMICALS INC (JP) 2015-02-25 EP disclosed
US-8888906-B2 Heat-sensitive color-developing composition and heat-sensitive recording material comprising the composition YAMAMOTO CHEMICALS, INC. (JP) 2014-11-18 US disclosed
US-8888906-B2 Heat-sensitive color-developing composition and heat-sensitive recording material comprising the composition YAMAMOTO CHEMICALS, INC. (JP) 2014-11-18 US disclosed
EP-2617578-A1 HEAT-SENSITIVE CHROMOGENIC COMPOSITION AND HEAT-SENSITIVE RECORDING MATERIAL FORMED USING SAID COMPOSITION Yamamoto Chemicals, Inc. (JP) 2013-07-24 EP disclosed
US-20130180430-A1 HEAT-SENSITIVE COLOR-DEVELOPING COMPOSITION AND HEAT-SENSITIVE RECORDING MATERIAL COMPRISING THE COMPOSITION YAMAMOTO CHEMICALS, INC. (JP) 2013-07-18 US disclosed
US-20130180430-A1 HEAT-SENSITIVE COLOR-DEVELOPING COMPOSITION AND HEAT-SENSITIVE RECORDING MATERIAL COMPRISING THE COMPOSITION YAMAMOTO CHEMICALS, INC. (JP) 2013-07-18 US disclosed
US-8129496-B2 Method for high density data storage and imaging INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2012-03-06 US disclosed
US-20080219135-A1 METHOD FOR HIGH DENSITY DATA STORAGE AND IMAGING GLOBALFOUNDRIES U.S. INC. 2008-09-11 US disclosed