Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 13/20 | 0.43 |
| ▸ | SPHK2 | Q9NRA0 | 7/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8448143 | 1.00 | SPHK1 (0.43) | SPHK1SPHK2DRD2CNR1MAOB | |
| SCHEMBL8455464 | 0.97 | SPHK1 (0.47) | SPHK1SPHK2DRD2 | |
| SCHEMBL8455469 | 0.97 | SPHK1 (0.47) | SPHK1SPHK2DRD2 | |
| SCHEMBL8447294 | 0.96 | SPHK1 (0.49) | SPHK1SPHK2 | |
| SCHEMBL8447296 | 0.96 | SPHK1 (0.49) | SPHK1SPHK2 | |
| SCHEMBL8452741 | 0.96 | SPHK1 (0.49) | SPHK1SPHK2 | |
| SCHEMBL8452744 | 0.96 | SPHK1 (0.49) | SPHK1SPHK2 | |
| SCHEMBL8448642 | 0.94 | SPHK1 (0.43) | SPHK1SPHK2 | |
| SCHEMBL8448638 | 0.94 | SPHK1 (0.43) | SPHK1SPHK2 | |
| SCHEMBL8454123 | 0.93 | DRD2 (0.39) | SPHK1DRD2CNR1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5858275-A | Chlorobenzene derivative and liquid crystal composition containing the same | CHISSO CORPORATION (JP) | 1999-01-12 | — | — | US | disclosed |
| EP-0785179-A1 | CHLOROBENZENE DERIVATIVE AND LIQUID-CRYSTAL COMPOSITION CONTAINING THE SAME | CHISSO CORPORATION (JP) | 1997-07-23 | — | — | EP | disclosed |