Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.32 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.32 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.32 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL129044 | 0.80 | DAO (0.45) | DAONPC1MAPTCASP3RAB9A | |
| SCHEMBL16548502 | 0.78 | NPC1 (0.38) | DAONPC1MAPTCASP3RAB9A | |
| SCHEMBL18256807 | 0.76 | DAO (0.32) | DAONPC1MAPTCASP3RAB9A | |
| SCHEMBL128138 | 0.73 | MLYCD (0.41) | DAOSMN1; SMN2 | |
| SCHEMBL14227644 | 0.72 | MAPK1 (0.39) | DAONPC1MAPTCASP3RAB9A | |
| SCHEMBL279712 | 0.72 | MAPK1 (0.39) | DAONPC1MAPTCASP3RAB9A | |
| SCHEMBL353045 | 0.70 | NPC1 (0.34) | DAONPC1MAPTCASP3RAB9A | |
| SCHEMBL23564899 | 0.68 | NPC1 (0.33) | DAONPC1MAPTCASP3RAB9A | |
| SCHEMBL16019420 | 0.68 | DAO (0.33) | DAONPC1MAPTCASP3RAB9A | |
| SCHEMBL128148 | 0.68 | MAPT (0.38) | DAONPC1MAPTCASP3RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0942909-A1 | BICYCLIC AMINE DERIVATIVES | ZENECA LIMITED (GB) | 1999-09-22 | — | — | EP | disclosed |
| WO-1998022463-A1 | BICYCLIC AMINE DERIVATIVES | ZENECA LIMITED (GB) | 1998-05-28 | — | — | WO | disclosed |