Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.62 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.62 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.62 |
| ▸ | EP300 | Q09472 | 5/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | TNF | P01375 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HBB | P68871 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8448237 | 1.00 | ALDH1A1 (0.62) | ALDH1A1KDM4EHPGDADRA1AHSD17B10 | |
| SCHEMBL8447891 | 1.00 | ALDH1A1 (0.62) | ALDH1A1KDM4EHPGDADRA1AHSD17B10 | |
| SCHEMBL8445433 | 0.93 | ALDH1A1 (0.60) | ALDH1A1KDM4EHPGDADRA1AHSD17B10 | |
| SCHEMBL8450131 | 0.93 | ALDH1A1 (0.60) | ALDH1A1KDM4EHPGDADRA1AHSD17B10 | |
| SCHEMBL8447898 | 0.93 | ALDH1A1 (0.60) | ALDH1A1KDM4EHPGDADRA1AHSD17B10 | |
| SCHEMBL8448248 | 0.93 | ALDH1A1 (0.60) | ALDH1A1KDM4EHPGDADRA1AHSD17B10 | |
| SCHEMBL8445432 | 0.93 | ALDH1A1 (0.60) | ALDH1A1KDM4EHPGDADRA1AHSD17B10 | |
| SCHEMBL8448247 | 0.93 | ALDH1A1 (0.60) | ALDH1A1KDM4EHPGDADRA1AHSD17B10 | |
| SCHEMBL8445384 | 0.93 | ALDH1A1 (0.60) | ALDH1A1KDM4EHPGDADRA1AHSD17B10 | |
| SCHEMBL8450129 | 0.93 | ALDH1A1 (0.60) | ALDH1A1KDM4EHPGDADRA1AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0942916-A2 | NUCLEOSIDES | Medivir Aktiebolag (SE) | 1999-09-22 | — | — | EP | disclosed |
| WO-1998021223-A1 | NUCLEOSIDES | MEDIVIR AB (SE) | 1998-05-22 | — | — | WO | disclosed |