Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | HTR2C | P28335 | 2/20 | 0.36 |
| ▸ | HTR2B | P41595 | 2/20 | 0.36 |
| ▸ | KDM1A | O60341 | 2/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | TLR4 | O00206 | 1/20 | 0.33 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 2/20 | 0.32 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9561975 | 1.00 | RIPK1 (0.39) | RIPK1HTR2AHTR2CHTR2BKDM1A | |
| SCHEMBL8448293 | 1.00 | RIPK1 (0.39) | RIPK1HTR2AHTR2CHTR2BKDM1A | |
| SCHEMBL8448300 | 1.00 | RIPK1 (0.39) | RIPK1HTR2AHTR2CHTR2BKDM1A | |
| SCHEMBL15445815 | 1.00 | RIPK1 (0.39) | RIPK1HTR2AHTR2CHTR2BKDM1A | |
| SCHEMBL24170502 | 0.97 | RIPK1 (0.41) | RIPK1HTR2AHTR2CHTR2BPDE4A | |
| SCHEMBL9924973 | 0.96 | HTR2C (0.37) | RIPK1HTR2AHTR2CHTR2BKDM1A | |
| SCHEMBL15445797 | 0.95 | RIPK1 (0.42) | RIPK1HTR2AHTR2CHTR2BKDM1A | |
| SCHEMBL12366402 | 0.95 | RIPK1 (0.42) | RIPK1HTR2AHTR2CHTR2BKDM1A | |
| SCHEMBL28700888 | 0.95 | RIPK1 (0.42) | RIPK1HTR2AHTR2CHTR2BKDM1A | |
| SCHEMBL9925083 | 0.93 | HTR2C (0.36) | RIPK1HTR2AHTR2CHTR2BKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5980778-A | STABILITY, COMPATIBILITY | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1999-11-09 | — | — | US | disclosed |
| EP-0768361-A1 | Liquid crystal composition and liquid crystal display element comprising the same | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1997-04-16 | — | — | EP | disclosed |
| US-5248447-A | 2,3-difluorohydroquinone derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1993-09-28 | — | — | US | disclosed |
| US-5143642-A | Thiadiazoles | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1992-09-01 | — | — | US | disclosed |