SCHEMBL8448333

SCHEMBL8448333

CCCCCCCCCCCCO[C](O)CC

nearest known ligand 0.58

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 1/20 0.58
CA12 O43570 3/20 0.50
CA1 P00915 3/20 0.50
CA2 P00918 3/20 0.50
CA9 Q16790 3/20 0.50
HCAR2 Q8TDS4 2/20 0.48
EPHX1 P07099 1/20 0.48
TSHR P16473 3/20 0.47
RAD52 P43351 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
MEN1 O00255 1/20 0.43
THRB P10828 1/20 0.43
HTT P42858 1/20 0.43
KMT2A Q03164 1/20 0.43
MAPT P10636 1/20 0.43
FAAH O00519 1/20 0.42
ALDH1A1 P00352 1/20 0.42
LMNA P02545 1/20 0.42
ACHE P22303 3/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL375009 1.00 NAAA (0.58) NAAACA12CA1CA2CA9
SCHEMBL17781743 0.90
SCHEMBL891412 0.83 NAAA (0.50) NAAACA12CA1CA2CA9
SCHEMBL27733980 0.80 TSHR (0.57) NAAACA12CA1CA2CA9
SCHEMBL4739657 0.80 TSHR (0.57) NAAACA12CA1CA2CA9
SCHEMBL27713564 0.80 TSHR (0.57) NAAACA12CA1CA2CA9
SCHEMBL11775344 0.80 TSHR (0.57) NAAACA12CA1CA2CA9
SCHEMBL6863758 0.80 TSHR (0.57) NAAACA12CA1CA2CA9
SCHEMBL6864269 0.80 TSHR (0.57) NAAACA12CA1CA2CA9
SCHEMBL246012 0.77 NAAA (0.60) NAAACA12CA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5880171-A A FREE RADICAL POLYMERIZABLE MONOMERS COMPRISE AN EPOXY OLIGOMER END TERMINATED WITH ACRYLATE OR METHACRYLATE, A DILUENT CONTAINING AN ACRYLIC OR METHACRYLIC ESTER OF HYDROCARBON DIOL AND AN ALKOXYLATED ACRYLATE OR POLYACRYLATE 2C OPTICS, INC. (US) 1999-03-09 US disclosed
EP-0636064-A4 LENSES WITH HIGH IMPACT RESISTANCE AND HIGH SCRATCH RESISTANCE. SOANE TECHNOLOGIES INC (US) 1998-07-01 EP disclosed
US-5667735-A ACRYLATED RESIN FILM, ABRASION RESISTANCE 2C OPTICS, INC. (US) 1997-09-16 US disclosed
EP-0636064-A1 LENSES WITH HIGH IMPACT RESISTANCE AND HIGH SCRATCH RESISTANCE SOANE TECHNOLOGIES INC. (US) 1995-02-01 EP disclosed
WO-1993021010-A1 LENSES WITH HIGH IMPACT RESISTANCE AND HIGH SCRATCH RESISTANCE SOANE TECHNOLOGIES, INC. (US) 1993-10-28 WO disclosed
EP-0471866-A1 Modified water-soluble cellulose ether Shin-Etsu Chemical Co., Ltd. (JP) 1992-02-26 EP disclosed