Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 13/20 | 0.86 |
| ▸ | ACE | P12821 | 13/20 | 0.86 |
| ▸ | FCER2 | P06734 | 3/20 | 0.51 |
| ▸ | CPA1 | P15085 | 1/20 | 0.47 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 3/20 | 0.43 |
| ▸ | MMP8 | P22894 | 2/20 | 0.43 |
| ▸ | MMP3 | P08254 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8029483 | 1.00 | MME (0.86) | MMEACEFCER2CPA1ACE2 | |
| SCHEMBL8032612 | 0.94 | MME (0.76) | MMEACEFCER2CPA1ACE2 | |
| SCHEMBL8018079 | 0.93 | MME (1.00) | MMEACECPA1ACE2 | |
| SCHEMBL8030485 | 0.93 | MME (1.00) | MMEACECPA1ACE2 | |
| SCHEMBL6440662 | 0.93 | MME (1.00) | MMEACECPA1ACE2 | |
| SCHEMBL8032890 | 0.93 | MME (1.00) | MMEACECPA1ACE2 | |
| SCHEMBL8027151 | 0.93 | MME (1.00) | MMEACECPA1ACE2 | |
| SCHEMBL6440665 | 0.93 | MME (1.00) | MMEACECPA1ACE2 | |
| SCHEMBL8033744 | 0.93 | MME (1.00) | MMEACECPA1ACE2 | |
| SCHEMBL8027474 | 0.92 | MME (0.74) | MMEACEFCER2CPA1ACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5891912-A | ENDOPEPTIDASE 24.11 INHIBITORS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1999-04-06 | — | — | US | disclosed |
| CN-1138321-A | 1, 3-dialkyl urea derivative with hydrocarbon group | SANTAN PHARMACEUTICAL CO LTD (JP) | 1996-12-18 | — | — | CN | disclosed |