Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 16/20 | 1.00 |
| ▸ | ACE | P12821 | 14/20 | 1.00 |
| ▸ | CPA1 | P15085 | 2/20 | 0.54 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.54 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6440665 | 1.00 | MME (1.00) | MMEACECPA1ACE2PIN1 | |
| SCHEMBL8033744 | 1.00 | MME (1.00) | MMEACECPA1ACE2PIN1 | |
| SCHEMBL8030485 | 1.00 | MME (1.00) | MMEACECPA1ACE2PIN1 | |
| SCHEMBL8032890 | 1.00 | MME (1.00) | MMEACECPA1ACE2PIN1 | |
| SCHEMBL8027151 | 1.00 | MME (1.00) | MMEACECPA1ACE2PIN1 | |
| SCHEMBL8018079 | 1.00 | MME (1.00) | MMEACECPA1ACE2PIN1 | |
| SCHEMBL8029483 | 0.93 | MME (0.86) | MMEACECPA1ACE2 | |
| SCHEMBL8027652 | 0.93 | MME (0.86) | MMEACECPA1ACE2PIN1 | |
| SCHEMBL8448452 | 0.93 | MME (0.86) | MMEACECPA1ACE2 | |
| SCHEMBL8027300 | 0.92 | MME (0.85) | MMEACECPA1ACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050070543-A1 | Compositions of a chromene or phenyl acetic acid cyclooxygenase-2 selective inhibitor and an ACE inhibitor for the treatment of central nervous system damage | PHARMACIA CORPORATION | 2005-03-31 | — | — | US | claimed |
| WO-2005016249-A2 | COMPOSITIONS OF A CHROMENE OR PHENYL ACETIC ACID CYCLOOXYGENASE-2 SELECTIVE INHIBITOR AND AN ACE INHIBITOR FOR THE TREATMENT OF CENTRAL NERVOUS SYSTEM DAMAGE | PHARMACIA CORPORATION (US) | 2005-02-24 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050070543-A1 | Compositions of a chromene or phenyl acetic acid cyclooxygenase-2 selective inhibitor and an ACE inhibitor for the treatment of central nervous system damage | ACE, ACE2, AGTR2 | MME 76/4885ACE 1/4885CPA1 25/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.