Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 17/20 | 0.60 |
| ▸ | CNR1 | P21554 | 10/20 | 0.60 |
| ▸ | GUCY1A1 | Q02108 | 1/20 | 0.58 |
| ▸ | GUCY1B1 | Q02153 | 1/20 | 0.58 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.51 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8448651 | 0.89 | GUCY1A1 (0.57) | CNR2CNR1GUCY1A1GUCY1B1SLC6A3 | |
| SCHEMBL8452079 | 0.85 | GUCY1A1 (0.57) | CNR2CNR1GUCY1A1GUCY1B1SLC6A3 | |
| SCHEMBL8452734 | 0.83 | GUCY1A1 (0.52) | CNR2CNR1GUCY1A1GUCY1B1SLC6A3 | |
| SCHEMBL8575121 | 0.81 | GUCY1A1 (0.50) | CNR2CNR1GUCY1A1GUCY1B1SLC6A3 | |
| SCHEMBL3897756 | 0.76 | GUCY1A1 (0.94) | CNR2CNR1GUCY1A1GUCY1B1SLC6A3 | |
| SCHEMBL8452077 | 0.75 | GUCY1A1 (0.55) | CNR2CNR1GUCY1A1GUCY1B1SLC6A3 | |
| SCHEMBL8452729 | 0.74 | GUCY1A1 (0.52) | CNR2CNR1GUCY1A1GUCY1B1TLR7 | |
| SCHEMBL8575119 | 0.72 | GUCY1A1 (0.49) | CNR2CNR1GUCY1A1GUCY1B1TLR7 | |
| SCHEMBL29989454 | 0.71 | CNR2 (1.00) | CNR2CNR1SLC6A3MEN1NR1I2 | |
| SCHEMBL29362163 | 0.70 | CNR2 (1.00) | CNR2CNR1SLC6A3MEN1NR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5856326-A | ANTITUMOR, ANTICANCER AGENTS | MERCK & CO., INC. (US) | 1999-01-05 | — | — | US | disclosed |