⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11748719 | 0.81 | ADH1B (0.32) | — | |
| SCHEMBL298107 | 0.77 | — | — | |
| SCHEMBL87987 | 0.73 | — | — | |
| SCHEMBL3958981 | 0.73 | — | — | |
| SCHEMBL5838433 | 0.71 | — | — | |
| SCHEMBL9441144 | 0.71 | — | — | |
| SCHEMBL19404347 | 0.71 | — | — | |
| SCHEMBL28566377 | 0.71 | TSHR (0.32) | — | |
| SCHEMBL1750243 | 0.69 | — | — | |
| SCHEMBL24668133 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015016729-A1 | UREA COMPOUNDS AND THEIR USE AS FAAH ENZYME INHIBITORS | BIAL - PORTELA & Cª, S.A. (PT) | 2015-02-05 | — | — | WO | claimed |
| EP-0102740-A1 | N-formyl and n-hydroxymethyl-3-phenoxy-1-azetidinecarboxamides and their preparation and use | A.H. ROBINS COMPANY, INCORPORATED (US) | 1984-03-14 | — | — | EP | claimed |
| WO-2015016729-A1 | UREA COMPOUNDS AND THEIR USE AS FAAH ENZYME INHIBITORS | BIAL - PORTELA & Cª, S.A. (PT) | 2015-02-05 | — | — | WO | disclosed |
| EP-0755387-B1 | OXIDATIVE PURIFICATION OF BIOMASS EXTRACTS CONTAINING TAXOL AND CEPHALOMANNINE USING OZONE AND GIRARD REAGENTS | HAUSER CHEMICAL RES INC (US) | 1999-08-04 | — | — | EP | disclosed |
| US-5792877-A | SEPARATING NON-OXIDIZABLE FROM OXIDIZABLE TAXANE DERIVATIVES | HAUSER CHEMICAL RESEARCH, INC. (US) | 1998-08-11 | — | — | US | disclosed |
| EP-0755387-A1 | OXIDATIVE PURIFICATION OF BIOMASS EXTRACTS CONTAINING TAXOL AND CEPHALOMANNINE USING OZONE AND GIRARD REAGENTS | HAUSER CHEMICAL RESEARCH, INC. (US) | 1997-01-29 | — | — | EP | disclosed |
| WO-1995027707-A1 | OXIDATIVE PURIFICATION OF BIOMASS EXTRACTS CONTAINING TAXOL AND CEPHALOMANNINE USING OZONE AND GIRARD REAGENTS | HAUSER CHEMICAL RESEARCH, INC. (US) | 1995-10-19 | — | — | WO | disclosed |
| US-5364947-A | Process for separating cephalomannine from taxol using ozone and water-soluble hydrazines or hydrazides | HAUSER CHEMICAL RESEARCH, INC. (US) | 1994-11-15 | — | — | US | disclosed |